ZNF207 产品
(Zinc Finger Protein 207 (ZNF207))
Categories
Kinetochore- and microtubule-binding protein that plays a key role in spindle assembly. ZNF207/BuGZ is mainly composed of disordered low-complexity regions and undergoes phase transition or coacervation to form temperature-dependent liquid droplets. Coacervation promotes microtubule bundling and concentrates tubulin, promoting microtubule polymerization and assembly of spindle and spindle matrix by concentrating its building blocks (PubMed:26388440). Also acts as a regulator of mitotic chromosome alignment by mediating the stability and kinetochore loading of to a first report, ZNF207/BuGZ may act by blocking ubiquitination and proteasomal degradation of BUB3. According to another report, the stabilization is independent of the proteasome (By similarity). {ECO:0000250|UniProtKB:O43670, ECO:0000269|PubMed:26388440}.
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Featured ZNF207 Categories
Recommended ZNF207 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, IHC (p)
Validations
- (6)
Cat. No.
ABIN563462
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, RNAi
Validations
- (6)
Cat. No.
ABIN563465
Quantity
100 μg
Datasheet
Datasheet
Reactivity
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Application
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Validations
- (4)
Cat. No.
ABIN563457
Quantity
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Datasheet
Datasheet
Recommended ZNF207 蛋白
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Reactivity
Source
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Human
Source
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- (1)
Cat. No.
ABIN1325975
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1325977
Quantity
10 μg
Datasheet
Datasheet
Reactivity
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Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN2735957
Quantity
20 μg
Datasheet
Datasheet
Latest Publications for our ZNF207 Products
: "Splicing function of mitotic regulators links R-loop-mediated DNA damage to tumor cell killing." in: The Journal of cell biology, Vol. 209, Issue 2, pp. 235-46, (2015) (PubMed).Synonyms and alternative names related to ZNF207
zinc finger protein 207 (Zfp207), zinc finger protein 207 (znf207), zinc finger protein 207 (ZNF207), zinc finger protein 207, b (znf207b), zinc finger protein 207 S homeolog (znf207.S), zinc finger protein 207, a (znf207a), 4m77, MGC75627, MGC116398, wu:fa03f07, wu:fb50g07, wu:fb51h09, wu:fc17a09, wu:fc17a10, wu:fj12e11, Zfp207, zgc:56601, zgc:77832, ZNF207, znf207Protein level used designations for ZNF207
- zinc finger protein 207
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