ZAP70 抗体
(zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70))
This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
recommended
recommended
ZAP70 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
recommended
ZAP70 适用: 人 IHC, ELISA, FACS, IF, StM, Coat 宿主: 小鼠 Monoclonal ZAP70-2035 unconjugated
ZAP70 抗体 by Grade
Find ZAP70 抗体 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.
ZAP70 抗体 by 抗体来源
Find ZAP70 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.
ZAP70 抗体 by 克隆形成能力
Find available monoclonal or polyclonal ZAP70 抗体. Click on a link to go to the corresponding products.
Popular ZAP70 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, FACS, ICC
Validations
- (1)
- (6)
Cat. No.
ABIN125756
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, ELISA, IF, ICC
Validations
- (8)
Cat. No.
ABIN6255884
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
IHC, ELISA, FACS, IF, StM, Coat
Validations
- (5)
Cat. No.
ABIN6940913
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, FACS
Validations
- (5)
Cat. No.
ABIN7193547
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (4)
Cat. No.
ABIN7439081
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
IHC, FACS, IF, StM
Validations
- (4)
Cat. No.
ABIN6940909
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, ELISA, IF, ICC
Validations
- (4)
Cat. No.
ABIN6256749
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (4)
Cat. No.
ABIN7193533
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
IHC, ELISA, StM, Coat
Validations
- (3)
Cat. No.
ABIN6940914
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (3)
Cat. No.
ABIN3023184
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF, IP
Validations
- (3)
Cat. No.
ABIN3023646
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, ELISA
Validations
- (3)
- (2)
Cat. No.
ABIN969464
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, FACS, IF, IHC (p)
Validations
- (2)
Cat. No.
ABIN4915233
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (2)
Cat. No.
ABIN7439084
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (2)
Cat. No.
ABIN6243970
Quantity
400 μL
Datasheet
Datasheet
Latest Publications for our ZAP70 抗体
: "Fibulin-3 may improve vascular health through inhibition of MMP-2/9 and oxidative stress in spontaneously hypertensive rats." in: Molecular medicine reports, Vol. 13, Issue 5, pp. 3805-12, (2017) (PubMed).: "Hypertensive vascular remodeling was inhibited by Xuezhikang through the regulation of Fibulin-3 and MMPs in spontaneously hypertensive rats." in: International journal of clinical and experimental medicine, Vol. 8, Issue 2, pp. 2118-27, (2015) (PubMed).
: "PRR7 is a transmembrane adaptor protein expressed in activated T cells involved in regulation of T cell receptor signaling and apoptosis." in: The Journal of biological chemistry, Vol. 286, Issue 22, pp. 19617-29, (2011) (PubMed).
: "ZAP-70 enhances B-cell-receptor signaling despite absent or inefficient tyrosine kinase activation in chronic lymphocytic leukemia and lymphoma B cells." in: Blood, Vol. 109, Issue 5, pp. 2032-9, (2007) (PubMed).
: "CTLA-4 disrupts ZAP70 microcluster formation with reduced T cell/APC dwell times and calcium mobilization." in: European journal of immunology, Vol. 38, Issue 1, pp. 40-7, (2007) (PubMed).
: "T cell activation-induced CrkII binding to the Zap70 protein tyrosine kinase is mediated by Lck-dependent phosphorylation of Zap70 tyrosine 315." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 175, Issue 12, pp. 8123-32, (2005) (PubMed).
: "Immunohistochemical analysis of ZAP-70 expression in B-cell lymphoid neoplasms." in: The Journal of pathology, Vol. 205, Issue 4, pp. 507-13, (2005) (PubMed).
: "[Everything you ever wanted to know about ZAP-70]." in: Médecine sciences : M/S, Vol. 21, Issue 2, pp. 150-5, (2005) (PubMed).
: "In vivo correction of ZAP-70 immunodeficiency by intrathymic gene transfer." in: The Journal of clinical investigation, Vol. 115, Issue 8, pp. 2287-95, (2005) (PubMed).
: "Evidence for the involvement of tyrosine kinase ZAP 70 in nuclear retinoid receptor-dependent transactivation in T lymphocytes." in: The Journal of biological chemistry, Vol. 280, Issue 40, pp. 34152-8, (2005) (PubMed).
Aliases for ZAP70 抗体
zeta chain of T-cell receptor associated protein kinase 70 (ZAP70) 抗体putative tyrosine-protein kinase zap-70 (Smp_149470) 抗体
zeta-chain (TCR) associated protein kinase (Zap70) 抗体
zeta chain of T cell receptor associated protein kinase 70 (Zap70) 抗体
zeta-chain (TCR) associated protein kinase 70kDa (ZAP70) 抗体
zeta chain of T cell receptor associated protein kinase 70kDa L homeolog (zap70.L) 抗体
zeta chain of T cell receptor associated protein kinase 70kDa (zap70) 抗体
zeta chain of T cell receptor associated protein kinase 70 (ZAP70) 抗体
tyrosine-protein kinase ZAP-70 (LOC707555) 抗体
tyrosine-protein kinase ZAP-70 (ZAP70) 抗体
tyrosine-protein kinase ZAP-70 (LOC100342021) 抗体
tyrosine-protein kinase ZAP-70 (LOC100390922) 抗体
tyrosine-protein kinase ZAP-70 (LOC100542877) 抗体
zeta-chain (TCR) associated protein kinase 70kDa (Zap70) 抗体
zeta-chain (TCR) associated protein kinase (zap70) 抗体
70kDa 抗体
AI327364 抗体
MGC80670 抗体
MGC88962 抗体
mrtle 抗体
mur 抗体
SRK 抗体
Srk 抗体
STCD 抗体
STD 抗体
TZK 抗体
ZAP-70 抗体
zap70 抗体
ZAP70 抗体
zgc:110383 抗体
您还需要查找其他产品吗？
You are here:
