ZAK 抗体
(Mitogen-Activated Protein Kinase Kinase Kinase MLT (ZAK))
This gene is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008].
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Popular ZAK 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, IHC (p)
Validations
- (3)
- (5)
Cat. No.
ABIN565679
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (4)
Cat. No.
ABIN6150360
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (3)
Cat. No.
ABIN565678
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (3)
Cat. No.
ABIN565680
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
ELISA, IHC
Validations
- (2)
Cat. No.
ABIN7249283
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (2)
Cat. No.
ABIN526926
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (2)
Cat. No.
ABIN565677
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IF, ICC
Validations
- (2)
Cat. No.
ABIN6259601
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (2)
Cat. No.
ABIN7268664
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (1)
- (2)
Cat. No.
ABIN392643
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (3)
Cat. No.
ABIN3032751
Quantity
0.4 mL
Datasheet
Datasheet
Reactivity
Mouse, Rat
Application
WB
Validations
- (1)
Cat. No.
ABIN7257916
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IF
Validations
- (1)
Cat. No.
ABIN3185591
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
Cat. No.
ABIN2854433
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IF, IC
Validations
- (2)
Cat. No.
ABIN7299644
Quantity
100 μL
Datasheet
Datasheet
Latest Publications for our ZAK 抗体
: "NEMO regulates a cell death switch in TNF signaling by inhibiting recruitment of RIPK3 to the cell death-inducing complex II." in: Cell death & disease, Vol. 7, Issue 8, pp. e2346, (2017) (PubMed).: "A Requirement for ZAK Kinase Activity in Canonical TGF-β Signaling." in: Translational oncology, Vol. 9, Issue 6, pp. 473-481, (2016) (PubMed).
: "Integrated exome and transcriptome sequencing reveals ZAK isoform usage in gastric cancer. ..." in: Nature communications, Vol. 5, pp. 3830, (2014) (PubMed).
: "A-kinase anchoring protein Lbc coordinates a p38 activating signaling complex controlling compensatory cardiac hypertrophy." in: Molecular and cellular biology, Vol. 33, Issue 15, pp. 2903-17, (2013) (PubMed).
: "A-kinase anchoring protein (AKAP)-Lbc anchors a PKN-based signaling complex involved in ?1-adrenergic receptor-induced p38 activation." in: The Journal of biological chemistry, Vol. 286, Issue 10, pp. 7925-37, (2011) (PubMed).
: "Phosphoinositide 3-kinase signalling pathways." in: Journal of cell science, Vol. 114, Issue Pt 8, pp. 1439-45, (2001) (PubMed).
: "Oncogenic kinase signalling." in: Nature, Vol. 411, Issue 6835, pp. 355-65, (2001) (PubMed).
: "The RET proto-oncogene in human cancers." in: Oncogene, Vol. 19, Issue 49, pp. 5590-7, (2000) (PubMed).
Aliases for ZAK 抗体
mitogen-activated protein kinase kinase kinase 20 (Map3k20) 抗体mitogen-activated protein kinase kinase kinase 20 (MAP3K20) 抗体
AV006891 抗体
AZK 抗体
B230120H23Rik 抗体
MLK7 抗体
mlklak 抗体
MLT 抗体
MLTK 抗体
MLTKalpha 抗体
MLTKbeta 抗体
MRK 抗体
pk 抗体
RGD1561394 抗体
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