XIAP 产品
(X-Linked Inhibitor of Apoptosis (XIAP))
Categories
This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-apoptotic function. This protein functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme. This protein also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7. Mutations in this gene are the cause of X-linked lymphoproliferative syndrome. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 2 and 11.[provided by RefSeq, Feb 2011].
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Featured XIAP Categories
XIAP 抗体
High quality antibodies with extensive validation data.
XIAP ELISA试剂盒
Reliable ELISA kits for a wide range of species.
XIAP 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended XIAP 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, IF, ICC
Validations
- (5)
Cat. No.
ABIN6256441
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, IHC (p), ICC
Validations
- (5)
Cat. No.
ABIN2854771
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro)
Validations
- (4)
- (3)
Cat. No.
ABIN674364
Quantity
100 μL
Datasheet
Datasheet
Recommended XIAP ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6960570
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6971208
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human, Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN625470
Quantity
96 tests
Datasheet
Datasheet
Recommended XIAP 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7125749
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7505227
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7417597
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our XIAP Products
: "Distinctive expression signatures of serum microRNAs in ischaemic stroke and transient ischaemic attack patients." in: Thrombosis and haemostasis, Vol. 117, Issue 5, pp. 992-1001, (2018) (PubMed).: "Phosphorylation of XIAP at threonine 180 controls its activity in Wnt signaling." in: Journal of cell science, Vol. 131, Issue 10, (2018) (PubMed).
: "Low-level light emitting diode (LED) therapy suppresses inflammasome-mediated brain damage in experimental ischemic stroke." in: Journal of biophotonics, (2017) (PubMed).
: "Protective Effects of Fucoidan on Aβ25-35 and d-Gal-Induced Neurotoxicity in PC12 Cells and d-Gal-Induced Cognitive Dysfunction in Mice." in: Marine drugs, Vol. 15, Issue 3, (2017) (PubMed).
: "Inactivation of BRCA2 in human cancer cells identifies a subset of tumors with enhanced sensitivity towards death receptor-mediated apoptosis." in: Oncotarget, Vol. 7, Issue 8, pp. 9477-90, (2017) (PubMed).
: "Mechanisms underlying 3-bromopyruvate-induced cell death in colon cancer." in: Journal of bioenergetics and biomembranes, (2015) (PubMed).
: "Gene transfection mediated by polyethyleneimine-polyethylene glycol nanocarrier prevents cisplatin-induced spiral ganglion cell damage." in: Neural regeneration research, Vol. 10, Issue 3, pp. 425-31, (2015) (PubMed).
: "Smac mimetic?induced caspase?independent necroptosis requires RIP1 in breast cancer." in: Molecular medicine reports, (2015) (PubMed).
: "Ampelopsin induces apoptosis by regulating multiple c?Myc/S?phase kinase?associated protein 2/F?box and WD repeat?containing protein 7/histone deacetylase 2 pathways in human lung adenocarcinoma ..." in: Molecular medicine reports, Vol. 11, Issue 1, pp. 105-12, (2014) (PubMed).
: "Wogonin has multiple anti-cancer effects by regulating c-Myc/SKP2/Fbw7? and HDAC1/HDAC2 pathways and inducing apoptosis in human lung adenocarcinoma cell line A549." in: PLoS ONE, Vol. 8, Issue 11, pp. e79201, (2013) (PubMed).
Synonyms and alternative names related to XIAP
X-linked inhibitor of apoptosis (XIAP), X-linked inhibitor of apoptosis (xiap), X-linked inhibitor of apoptosis L homeolog (xiap.L), X-linked inhibitor of apoptosis (Xiap), 1110015C02Rik, Aipa, API3, api3, Api3, BIRC4, birc4, Birc4, BIRC8, fb73d01, hIAP-3, hIAP3, IAP-3, IAP3, ILP-1, ILP1, ilp1, MIHA, miha, mXIAP, riap3, wu:fb73d01, XLP2, xlp2, xxiap, zgc:91873Protein level used designations for XIAP
- E3 ubiquitin-protein ligase XIAP
- IAP-like protein
- X-linked IAP
- baculoviral IAP repeat-containing protein 4
- inhibitor of apoptosis protein 3
- Baculoviral IAP repeat-containing protein 4
- X-linked inhibitor of apoptosis protein
- baculoviral IAP repeat-containing 4
- baculoviral IAP-repeat containing protein 4
- IAP homolog A
- IAP-3
- apoptosis inhibitor 3
- mIAP-3
- mIAP3
- RIAP-3
- apoptosis inhibitor protein 3
- baculoviral IAP repeat containing 8
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