WTIP 产品
(Wilms Tumor 1 Interacting Protein (WTIP))
Categories
Adapter or scaffold protein which participates in the assembly of numerous protein complexes and is involved in several cellular processes such as cell fate determination, cytoskeletal organization, repression of gene transcription, cell-cell adhesion, cell differentiation, proliferation and migration. Positively regulates microRNA (miRNA)-mediated gene silencing. Negatively regulates Hippo signaling pathway and antagonizes phosphorylation of YAP1. Acts as a transcriptional corepressor for SNAI1 and SNAI2/SLUG-dependent repression of E-cadherin transcription. Acts as a hypoxic regulator by bridging an association between the prolyl hydroxylases and VHL enabling efficient degradation of HIF1A. May monitor slit diaphragm protein assembly, a specialized adherens junction characteristic of podocytes. In case of podocyte injury, it shuttles into the nucleus and acts as a transcription regulator that represses WT1- dependent transcription regulation, thereby translating changes in slit diaphragm structure into altered gene expression and a less differentiated phenotype.
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Featured WTIP Categories
WTIP 抗体
High quality antibodies with extensive validation data.
WTIP ELISA试剂盒
Reliable ELISA kits for a wide range of species.
WTIP 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended WTIP 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (4)
Cat. No.
ABIN1327433
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (2)
Cat. No.
ABIN1327034
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, IHC (p)
Validations
- (3)
Cat. No.
ABIN655782
Quantity
400 μL
Datasheet
Datasheet
Recommended WTIP ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6971180
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1167480
Quantity
96 tests
Datasheet
Datasheet
Recommended WTIP 蛋白
Synonyms and alternative names related to WTIP
WT1 interacting protein (Wtip), WT1 interacting protein (WTIP), WT1 interacting protein (wtip), Wilms tumor 1 interacting protein (WTIP), WT1 interacting protein L homeolog (wtip.L), WT1-interacting protein (Wtip), RGD1306411, si:ch211-79l17.3Protein level used designations for WTIP
- WT1-interacting protein
- Wilms tumor protein 1-interacting protein
- Wilms tumor protein 1-interacting protein homolog
- WT1-interacting protein homolog
- Wilms tumor 1 interacting protein
- xWtip
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