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WNT5A 产品

(Wingless-Type MMTV Integration Site Family, Member 5A (WNT5A))

Categories

The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene encodes a member of the WNT family that signals through both the canonical and non-canonical WNT pathways. This protein is a ligand for the seven transmembrane receptor frizzled-5 and the tyrosine kinase orphan receptor 2. This protein plays an essential role in regulating developmental pathways during embryogenesis. This protein may also play a role in oncogenesis. Mutations in this gene are the cause of autosomal dominant Robinow syndrome. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012].

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Featured WNT5A Categories

WNT5A 抗体

High quality antibodies with extensive validation data.

WNT5A ELISA试剂盒

Reliable ELISA kits for a wide range of species.

WNT5A 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended WNT5A 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Dog, Human, Mouse, Rat
Application WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
  • (3)
  • (6)
Cat. No. ABIN675758
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, FACS, IHC (p)
Validations
  • (1)
  • (6)
Cat. No. ABIN651869
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA, IF
Validations
  • (4)
Cat. No. ABIN7166304
Quantity 100 μg
Datasheet Datasheet

Recommended WNT5A ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (10)
  • (5)
Cat. No. ABIN6574332
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (1)
Cat. No. ABIN6960551
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6971194
Quantity 96 tests
Datasheet Datasheet

Recommended WNT5A 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1325364
Quantity 25 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1325365
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7539360
Quantity 25 μg
Datasheet Datasheet

Latest Publications for our WNT5A Products

Akoumianakis, Sanna, Margaritis, Badi, Akawi, Herdman, Coutinho, Fagan, Antonopoulos, Oikonomou, Thomas, Chiu, Chuaiphichai, Kotanidis, Christodoulides, Petrou, Krasopoulos, Sayeed, Lv, Hale et al.: "Adipose tissue-derived WNT5A regulates vascular redox signaling in obesity via USP17/RAC1-mediated activation of NADPH oxidases. ..." in: Science translational medicine, Vol. 11, Issue 510, (2020) (PubMed).

Asem, Young, Oyama, Claure De La Zerda, Liu, Yang, Hilliard, Johnson, Harper, Guldner, Zhang, Page-Mayberry, Kaliney, Stack: "Host Wnt5a Potentiates Microenvironmental Regulation of Ovarian Cancer Metastasis." in: Cancer research, Vol. 80, Issue 5, pp. 1156-1170, (2020) (PubMed).

Abraityte, Lunde, Askevold, Michelsen, Christensen, Aukrust, Yndestad, Fiane, Andreassen, Aakhus, Dahl, Gullestad, Broch, Ueland: "Wnt5a is associated with right ventricular dysfunction and adverse outcome in dilated cardiomyopathy." in: Scientific reports, Vol. 7, Issue 1, pp. 3490, (2019) (PubMed).

Fultang, Illendula, Chen, Wu, Jonnalagadda, Baird, Klase, Peethambaran: "Strictinin, a novel ROR1-inhibitor, represses triple negative breast cancer survival and migration via modulation of PI3K/AKT/GSK3ß activity." in: PLoS ONE, Vol. 14, Issue 5, pp. e0217789, (2019) (PubMed).

Wu, Xiong, Wang, Miao, Liu, Li, Zou, Liu, Zhao, Yang: "Comparative study of ROR2 and WNT5a expression in squamous/adenosquamous carcinoma and adenocarcinoma of the gallbladder." in: World journal of gastroenterology, Vol. 23, Issue 14, pp. 2601-2612, (2018) (PubMed).

Zerboni, Sung, Lee, Arvin: "Age-Associated Differences in Infection of Human Skin in the SCID Mouse Model of Varicella-Zoster Virus Pathogenesis." in: Journal of virology, Vol. 92, Issue 11, (2018) (PubMed).

Xu, Li, Cole, Sherman, Du: "Reduced Cell Division Control Protein 42 Activity Compromises Hematopoiesis-Supportive Function of Fanconi Anemia Mesenchymal Stromal Cells." in: Stem cells (Dayton, Ohio), Vol. 36, Issue 5, pp. 785-795, (2018) (PubMed).

Cho, Kang, Lee, Lee, Seol, Lee, Park, Jung: "Effect of SFRP5 (Secreted Frizzled-Related Protein 5) on the WNT5A (Wingless-Type Family Member 5A)-Induced Endothelial Dysfunction and Its Relevance With Arterial Stiffness in Human Subjects." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 38, Issue 6, pp. 1358-1367, (2018) (PubMed).

Prgomet, Andersson, Lindberg: "Optimization, validation, and identification of two reliable antibodies for immunodetection of WNT5A." in: Biotechnic & histochemistry : official publication of the Biological Stain Commission, Vol. 92, Issue 1, pp. 46-58, (2017) (PubMed).

Zaghloul, Elsherbiny, Kenawy, El-Karef, Eissa, El-Shishtawy: "Hepatoprotective effect of hesperidin in hepatocellular carcinoma: Involvement of Wnt signaling pathways." in: Life sciences, Vol. 185, pp. 114-125, (2017) (PubMed).

Synonyms and alternative names related to WNT5A

Wnt family member 5A (WNT5A), Wnt family member 5A (Wnt5a), Wnt family member 5A S homeolog (wnt5a.S), wingless-type MMTV integration site family, member 5a (wnt5a), wingless-type MMTV integration site family, member 5A (Wnt5a), wingless-related MMTV integration site 5A (LOC578814), Wnt signaling ligand (wnt5), 8030457G12Rik, hWNT5A, wnt-5A, Wnt-5a, WNT5A, wnt5a-B

Protein level used designations for WNT5A

  • WNT-5A protein
  • protein Wnt-5a
  • Wnt-5a protein
  • wingless-related MMTV integration site 5A
  • wingless-type MMTV integration site 5A
  • XWnt-5a
  • Wnt-5a
  • wingless-type MMTV integration site family, member 5A
  • protein Wnt-5a-like
  • cell signaling molecule Wnt-5
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