WNT1 产品
(Wingless-Type MMTV Integration Site Family, Member 1 (WNT1))
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The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is very conserved in evolution, and the protein encoded by this gene is known to be 98% identical to the mouse Wnt1 protein at the amino acid level. The studies in mouse indicate that the Wnt1 protein functions in the induction of the mesencephalon and cerebellum. This gene was originally considered as a candidate gene for Joubert syndrome, an autosomal recessive disorder with cerebellar hypoplasia as a leading feature. However, further studies suggested that the gene mutations might not have a significant role in Joubert syndrome. This gene is clustered with another family member, WNT10B, in the chromosome 12q13 region. [provided by RefSeq, Jul 2008].
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Featured WNT1 Categories
WNT1 抗体
High quality antibodies with extensive validation data.
WNT1 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
WNT1 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended WNT1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (7)
Cat. No.
ABIN1683291
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
- (4)
- (4)
Cat. No.
ABIN733748
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, IF, ICC
Validations
- (1)
- (4)
Cat. No.
ABIN6266035
Quantity
100 μL
Datasheet
Datasheet
Recommended WNT1 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6960531
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6971182
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6960532
Quantity
96 tests
Datasheet
Datasheet
Recommended WNT1 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7125731
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7386137
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our WNT1 Products
: "Wnt1 inhibits vascular smooth muscle cell calcification by promoting ANKH expression." in: Journal of molecular and cellular cardiology, Vol. 135, pp. 10-21, (2020) (PubMed).: "Neoisoliquiritigenin Inhibits Tumor Progression by Targeting GRP78-β- catenin Signaling in Breast Cancer." in: Current cancer drug targets, Vol. 18, Issue 4, pp. 390-399, (2018) (PubMed).
: "Combined therapy with melatonin and exendin-4 effectively attenuated the deterioration of renal function in rat cardiorenal syndrome." in: American journal of translational research, Vol. 9, Issue 2, pp. 214-229, (2017) (PubMed).
: "Docosahexaenoic acid inhibits 12-O-tetradecanoylphorbol-13- acetate-induced fascin-1-dependent breast cancer cell migration by suppressing the PKCδ- and Wnt-1/β-catenin-mediated pathways." in: Oncotarget, Vol. 7, Issue 18, pp. 25162-79, (2016) (PubMed).
: "Wnt/β-catenin pathway is required for epithelial to mesenchymal transition in CXCL12 over expressed breast cancer cells." in: International journal of clinical and experimental pathology, Vol. 8, Issue 10, pp. 12357-67, (2016) (PubMed).
: "Evaluation of RECIST in chemotherapy-treated lung cancer: the Pharmacogenoscan Study." in: BMC cancer, Vol. 14, pp. 989, (2015) (PubMed).
: "Salvianolic acid B improves bone marrow-derived mesenchymal stem cell differentiation into alveolar epithelial cells type I via Wnt signaling." in: Molecular medicine reports, Vol. 12, Issue 2, pp. 1971-6, (2015) (PubMed).
: "MicroRNA-139-5p regulates C2C12 cell myogenesis through blocking Wnt/β-catenin signaling pathway." in: Biochemistry and cell biology = Biochimie et biologie cellulaire, Vol. 93, Issue 1, pp. 8-15, (2015) (PubMed).
: "Wnt pathway activation in long term remnant rat model." in: BioMed research international, Vol. 2014, pp. 324713, (2015) (PubMed).
: "Comparative study of Hsp27, GSK3?, Wnt1 and PRDX3 in Hirschsprung's disease." in: International journal of experimental pathology, Vol. 95, Issue 3, pp. 229-37, (2014) (PubMed).
Synonyms and alternative names related to WNT1
Wnt family member 1 (WNT1), Wnt family member 1 L homeolog (wnt1.L), wingless-type MMTV integration site family, member 1 (Wnt1), Wnt family member 1 (Wnt1), wingless-type MMTV integration site family, member 1 (wnt1), BMND16, int-1, Int-1, int1, INT1, Int1, OI15, sb:eu647, sw, swaying, wnt-1, Wnt-1, WNT-1, WNT1, wnt1-a, Xint-1, Xwnt1, zgc:194464, zgc:194478Protein level used designations for WNT1
- XWnt-1
- protein Wnt-1
- proto-oncogene Int-1
- proto-oncogene Wnt-1
- proto-oncogene protein Wnt-1
- proto-oncogene Int-1 homolog
- wingless-type MMTV integration site family, member 1 (oncogene INT1)
- Wingless-type MMTV integration site 1 homolog
- Wingless-type MMTV integration site 1, homolog
- wingless-related MMTV integration site 1
- murine mammary tumor virus integration site
- etID22400.23
- wingless-type MMTV integration site family member 1
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