WISP1 抗体
(WNT1 Inducible Signaling Pathway Protein 1 (WISP1))
This gene encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like domain. This gene may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. It is expressed at a high level in fibroblast cells, and overexpressed in colon tumors. The encoded protein binds to decorin and biglycan, two members of a family of small leucine-rich proteoglycans present in the extracellular matrix of connective tissue, and possibly prevents the inhibitory activity of decorin and biglycan in tumor cell proliferation. It also attenuates p53-mediated apoptosis in response to DNA damage through activation of the Akt kinase. It is 83% identical to the mouse protein at the amino acid level. Multiple alternatively spliced transcript variants have been identified. [provided by RefSeq, Mar 2011].
recommended
Verified WISP1 适用: 人 WB, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
recommended
recommended
WISP1 抗体 by Grade
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WISP1 抗体 by 适用
Find WISP1 抗体 for a variety of species such as anti-Human WISP1, anti-Mouse WISP1, anti-Rat WISP1. The species listed below are among those available. Click on a link to go to the corresponding products.
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WISP1 抗体 by 克隆形成能力
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Popular WISP1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, FACS
Validations
- (7)
Cat. No.
ABIN238610
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (5)
Cat. No.
ABIN7436372
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, ELISA, IF
Validations
- (4)
Cat. No.
ABIN7175846
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ICC, IHC (p), IHC (fro)
Validations
- (5)
Cat. No.
ABIN3043974
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p), IF
Validations
- (3)
Cat. No.
ABIN522291
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Mouse
Application
ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
- (1)
- (1)
Cat. No.
ABIN872843
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
WB, IHC, IP, ICC
Validations
- (2)
Cat. No.
ABIN7441403
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC
Validations
- (2)
Cat. No.
ABIN6266028
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (2)
Cat. No.
ABIN1683290
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, ICC
Validations
- (3)
Cat. No.
ABIN1176562
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (1)
- (2)
Cat. No.
ABIN390187
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Cow, Human, Pig
Application
WB
Validations
- (2)
Cat. No.
ABIN2789653
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p), EIA
Validations
- (2)
Cat. No.
ABIN358745
Quantity
0.4 mL
Datasheet
Datasheet
Reactivity
Mouse
Application
ELISA, IHC (p), IHC (fro)
Validations
Cat. No.
ABIN920004
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse
Application
IF (cc), IF (p)
Validations
Cat. No.
ABIN5012500
Quantity
100 μL
Datasheet
Datasheet
Latest Publications for our WISP1 抗体
: "Tao-Hong-Si-Wu Decoction promotes angiogenesis after cerebral ischaemia in rats via platelet microparticles." in: Chinese journal of natural medicines, Vol. 18, Issue 8, pp. 620-627, (2020) (PubMed).: "Resveratrol Attenuates Hyperoxia-induced Oxidative Stress, Inflammation and Fibrosis and Suppresses Wnt/?-catenin Signaling in Lungs of Neonatal Rats." in: Clinical and experimental pharmacology & physiology, (2015) (PubMed).
: "WISP-2 in human gastric cancer and its potential metastatic suppressor role in gastric cancer cells mediated by JNK and PLC-? pathways." in: British journal of cancer, Vol. 113, Issue 6, pp. 921-33, (2015) (PubMed).
: "Wilms tumor suppressor WTX negatively regulates WNT/beta-catenin signaling." in: Science (New York, N.Y.), Vol. 316, Issue 5827, pp. 1043-6, (2007) (PubMed).
: "Overexpression of WISP-1 down-regulated motility and invasion of lung cancer cells through inhibition of Rac activation." in: The Journal of biological chemistry, Vol. 278, Issue 13, pp. 11465-70, (2003) (PubMed).
: "Human WISP1v, a member of the CCN family, is associated with invasive cholangiocarcinoma." in: Hepatology (Baltimore, Md.), Vol. 37, Issue 5, pp. 1122-9, (2003) (PubMed).
: "Regulation of the Wnt signaling pathway by disabled-2 (Dab2)." in: The EMBO journal, Vol. 22, Issue 12, pp. 3084-94, (2003) (PubMed).
: "WISP genes are members of the connective tissue growth factor family that are up-regulated in wnt-1-transformed cells and aberrantly expressed in human colon tumors." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 95, Issue 25, pp. 14717-22, (1999) (PubMed).
Aliases for WISP1 抗体
WNT1 inducible signaling pathway protein 1 (WISP1) 抗体WNT1 inducible signaling pathway protein 1a (wisp1a) 抗体
WNT1 inducible signaling pathway protein 1 (Wisp1) 抗体
WNT1-inducible-signaling pathway protein 1-like (LOC100627044) 抗体
WNT1 inducible signaling pathway protein 1b (wisp1b) 抗体
AW146261 抗体
CCN4 抗体
Elm1 抗体
si:ch211-38f10.2 抗体
WISP-1 抗体
WISP1 抗体
WISP1c 抗体
WISP1i 抗体
WISP1tc 抗体
zgc:172276 抗体
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