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WDR11 产品

(WD Repeat Domain 11 (WDR11))

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This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is located in the chromosome 10q25-26 region, which is frequently deleted in gliomas and tumors of other tissues, and is disrupted by the t(10\;19) translocation rearrangement in glioblastoma cells. The gene location suggests that it is a candidate gene for the tumor suppressor locus. [provided by RefSeq, Jul 2008].

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Featured WDR11 Categories

WDR11 抗体

High quality antibodies with extensive validation data.

Recommended WDR11 抗体

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Cat. No. ABIN965702
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Recommended WDR11 蛋白

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Source Tobacco (Nicotiana tabacum)
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Latest Publications for our WDR11 Products

Chernova, Hunyadi, Malaj, Pan, Crooks, Roe, Cowell: "A novel member of the WD-repeat gene family, WDR11, maps to the 10q26 region and is disrupted by a chromosome translocation in human glioblastoma cells." in: Oncogene, Vol. 20, Issue 38, pp. 5378-92, (2001) (PubMed).

Synonyms and alternative names related to WDR11

WD repeat domain 11 (Wdr11), WD repeat domain 11 (WDR11), 2900055P10Rik, AW489876, Brwd2, BRWD2, DR11, HH14, mKIAA1351, PHIP, WDR11, WDR15

Protein level used designations for WDR11

  • WD repeat-containing protein 11
  • bromodomain and WD repeat domain containing 2
  • WD40 repeat domain 11
  • pleckstrin homology domain interacting protein
  • WD repeat domain 11
  • WD repeat domain 15
  • WD repeat-containing protein 15
  • bromodomain and WD repeat-containing protein 2
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