Utrophin 产品
(Utrophin (UTRN))
Categories
This gene shares both structural and functional similarities with the dystrophin gene. It contains an actin-binding N-terminus, a triple coiled-coil repeat central region, and a C-terminus that consists of protein-protein interaction motifs which interact with dystroglycan protein components. The protein encoded by this gene is located at the neuromuscular synapse and myotendinous junctions, where it participates in post-synaptic membrane maintenance and acetylcholine receptor clustering. Mouse studies suggest that this gene may serve as a functional substitute for the dystrophin gene and therefore, may serve as a potential therapeutic alternative to muscular dystrophy which is caused by mutations in the dystrophin gene. Alternative splicing of the utrophin gene has been described\; however, the full-length nature of these variants has not yet been determined. [provided by RefSeq, Jul 2008].
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Featured Utrophin Categories
Utrophin 抗体
High quality antibodies with extensive validation data.
Utrophin ELISA试剂盒
Reliable ELISA kits for a wide range of species.
Utrophin 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Utrophin 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (8)
Cat. No.
ABIN7443953
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (3)
Cat. No.
ABIN563360
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
Cat. No.
ABIN563359
Quantity
50 μL
Datasheet
Datasheet
Recommended Utrophin ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6971089
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6960406
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6960407
Quantity
96 tests
Datasheet
Datasheet
Recommended Utrophin 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1324869
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7417648
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7408324
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our Utrophin Products
: "Muscle and neural isoforms of agrin increase utrophin expression in cultured myotubes via a transcriptional regulatory mechanism." in: The Journal of biological chemistry, Vol. 273, Issue 2, pp. 736-43, (1998) (PubMed).: "Utrophin-dystrophin-deficient mice as a model for Duchenne muscular dystrophy." in: Cell, Vol. 90, Issue 4, pp. 717-27, (1997) (PubMed).
: "Skeletal and cardiac myopathies in mice lacking utrophin and dystrophin: a model for Duchenne muscular dystrophy." in: Cell, Vol. 90, Issue 4, pp. 729-38, (1997) (PubMed).
: "Cloning and expression of full length mouse utrophin: the differential association of utrophin and dystrophin with AChR clusters." in: FEBS letters, Vol. 398, Issue 2-3, pp. 259-64, (1997) (PubMed).
: "Primary structure of dystrophin-related protein." in: Nature, Vol. 360, Issue 6404, pp. 591-3, (1993) (PubMed).
Synonyms and alternative names related to Utrophin
utrophin L homeolog (utrn.L), utrophin (UTRN), utrophin (LOAG_03796), utrophin (utrn), utrophin (LOC100551145), utrophin (Utrn), AA589569, DKFZp469A0710, dmdl, DMDL, Dmdl, drp, DRP, drp1, DRP1Protein level used designations for Utrophin
- utrophin
- utrophin, or dystrophin-related protein 1
- DRP-1
- dystrophin-related protein 1
- utrophin (homologous to dystrophin)
- G-utrophin
- urotrophin
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