USP2 抗体
(Ubiquitin Specific Peptidase 2 (USP2))
This gene encodes a member of the family of de-ubiquitinating enzymes, which belongs to the peptidase C19 superfamily. The encoded protein is a ubiquitin-specific protease which is required for TNF-alpha (tumor necrosis factor alpha) -induced NF-kB (nuclear factor kB) signaling. This protein deubiquitinates polyubiquitinated target proteins such as fatty acid synthase, murine double minute 2 (MDM2), MDM4/MDMX and cyclin D1. MDM2 and MDM4 are negative regulators of the p53 tumor suppressor and cyclin D1 is required for cell cycle G1/S transition. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011].
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USP2 抗体 by 应用范围
Find USP2 抗体 validated for a specific application such as WB, ELISA, IHC, IHC (p). Some of the available applications are listed below. Click on a link to go to the corresponding products.
USP2 抗体 by 抗体来源
Find USP2 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.
USP2 抗体 by 克隆形成能力
Find available monoclonal or polyclonal USP2 抗体. Click on a link to go to the corresponding products.
USP2 抗体 by 克隆
Find USP2 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.
USP2 抗体 by 标记
Find USP2 抗体 with a specific conjugate such as FITC, Biotin, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.
Popular USP2 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (12)
- (4)
Cat. No.
ABIN388879
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human, Rat
Application
WB, IHC (p)
Validations
- (4)
- (4)
Cat. No.
ABIN388877
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC
Validations
- (2)
Cat. No.
ABIN7174279
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
ELISA, IHC
Validations
- (2)
Cat. No.
ABIN7236025
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IP
Validations
- (2)
Cat. No.
ABIN948772
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IF
Validations
- (1)
Cat. No.
ABIN7174280
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Green Monkey, Human
Application
WB
Validations
- (1)
Cat. No.
ABIN6244029
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
Validations
- (3)
Cat. No.
ABIN1882149
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
Cat. No.
ABIN522543
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Cow, Dog, Human, Monkey, Rat
Application
WB
Validations
- (1)
Cat. No.
ABIN6746576
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Dog, Horse, Human, Monkey, Rabbit
Application
WB, IHC, IHC (p)
Validations
- (1)
Cat. No.
ABIN6756666
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application
WB, IHC
Validations
- (2)
Cat. No.
ABIN2788020
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
Application
WB
Validations
- (2)
Cat. No.
ABIN2788021
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
Cat. No.
ABIN7091801
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA
Validations
Cat. No.
ABIN7174285
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our USP2 抗体
: "Ubiquitin-Specific Protease 2 Modulates the Lipopolysaccharide-Elicited Expression of Proinflammatory Cytokines in Macrophage-like HL-60 Cells." in: Mediators of inflammation, Vol. 2017, pp. 6909415, (2018) (PubMed).: "Deubiquitinase USP2a Sustains Interferons Antiviral Activity by Restricting Ubiquitination of Activated STAT1 in the Nucleus." in: PLoS pathogens, Vol. 12, Issue 7, pp. e1005764, (2017) (PubMed).
: "Small Molecule Inhibition of the Ubiquitin-specific Protease USP2 Accelerates cyclin D1 Degradation and Leads to Cell Cycle Arrest in Colorectal Cancer and Mantle Cell Lymphoma Models." in: The Journal of biological chemistry, Vol. 291, Issue 47, pp. 24628-24640, (2017) (PubMed).
: "Overexpression of ubiquitin-specific protease 2a (USP2a) and nuclear factor erythroid 2-related factor 2 (Nrf2) in human gliomas." in: Journal of the neurological sciences, Vol. 363, pp. 249-52, (2016) (PubMed).
: "Ubiquitin-specific protease 2b negatively regulates IFN-? production and antiviral activity by targeting TANK-binding kinase 1." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 193, Issue 5, pp. 2230-7, (2014) (PubMed).
: "Ubiquitin-specific protease 2-69 in macrophages potentially modulates metainflammation." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 27, Issue 12, pp. 4940-53, (2013) (PubMed).
: "USP2a protein deubiquitinates and stabilizes the circadian protein CRY1 in response to inflammatory signals." in: The Journal of biological chemistry, Vol. 287, Issue 30, pp. 25280-91, (2012) (PubMed).
: "Ubiquitination-deubiquitination balance dictates ligand-stimulated PTHR sorting." in: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Vol. 26, Issue 12, pp. 2923-34, (2011) (PubMed).
: "Mice lacking the USP2 deubiquitinating enzyme have severe male subfertility associated with defects in fertilization and sperm motility." in: Biology of reproduction, Vol. 85, Issue 3, pp. 594-604, (2011) (PubMed).
: "Ubiquitin-specific protease 2-45 (Usp2-45) binds to epithelial Na+ channel (ENaC)-ubiquitylating enzyme Nedd4-2." in: American journal of physiology. Renal physiology, Vol. 301, Issue 1, pp. F189-96, (2011) (PubMed).
Aliases for USP2 抗体
ubiquitin specific peptidase 2 (USP2) 抗体ubiquitin specific peptidase 2 (Usp2) 抗体
ubiquitin specific peptidase 2a (usp2a) 抗体
B930035K21Rik 抗体
UBP-t 抗体
UBP41 抗体
Ubp41 抗体
UBP46 抗体
ubp52 抗体
ubp66 抗体
USP9 抗体
zgc:92134 抗体
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