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USP2 抗体

(Ubiquitin Specific Peptidase 2 (USP2))
This gene encodes a member of the family of de-ubiquitinating enzymes, which belongs to the peptidase C19 superfamily. The encoded protein is a ubiquitin-specific protease which is required for TNF-alpha (tumor necrosis factor alpha) -induced NF-kB (nuclear factor kB) signaling. This protein deubiquitinates polyubiquitinated target proteins such as fatty acid synthase, murine double minute 2 (MDM2), MDM4/MDMX and cyclin D1. MDM2 and MDM4 are negative regulators of the p53 tumor suppressor and cyclin D1 is required for cell cycle G1/S transition. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011].
USP2 抗体  (C-Term) USP2 抗体  (C-Term) USP2 抗体 (C-Term) (ABIN388879)

USP2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB4417 unconjugated

USP2 抗体  (N-Term) USP2 抗体  (N-Term) USP2 抗体 (N-Term) (ABIN388877)

USP2 适用: 人, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB4202 unconjugated

USP2 抗体  (C-Term) USP2 抗体  (C-Term) USP2 抗体 (C-Term) (ABIN7174279)

USP2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated

USP2 抗体 by 适用

Find USP2 抗体 for a variety of species such as anti-Human USP2, anti-Mouse USP2, anti-Rat USP2. The species listed below are among those available. Click on a link to go to the corresponding products.

USP2 抗体 by 应用范围

Find USP2 抗体 validated for a specific application such as WB, ELISA, IHC, IHC (p). Some of the available applications are listed below. Click on a link to go to the corresponding products.

USP2 抗体 by 抗体来源

Find USP2 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

USP2 抗体 by 抗原表位

Find USP2 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

USP2 抗体 by 克隆形成能力

Find available monoclonal or polyclonal USP2 抗体. Click on a link to go to the corresponding products.

USP2 抗体 by 克隆

Find USP2 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

USP2 抗体 by 标记

Find USP2 抗体 with a specific conjugate such as FITC, Biotin, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular USP2 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (12)
  • (4)
Cat. No. ABIN388879
Quantity 400 μL
Datasheet Datasheet
Reactivity Human, Rat
Application WB, IHC (p)
Validations
  • (4)
  • (4)
Cat. No. ABIN388877
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7174279
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7236025
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, IP
Validations
  • (2)
Cat. No. ABIN948772
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IF
Validations
  • (1)
Cat. No. ABIN7174280
Quantity 100 μg
Datasheet Datasheet
Reactivity Green Monkey, Human
Application WB
Validations
  • (1)
Cat. No. ABIN6244029
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application
Validations
  • (3)
Cat. No. ABIN1882149
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN522543
Quantity 50 μg
Datasheet Datasheet
Reactivity Cow, Dog, Human, Monkey, Rat
Application WB
Validations
  • (1)
Cat. No. ABIN6746576
Quantity 100 μL
Datasheet Datasheet
Reactivity Dog, Horse, Human, Monkey, Rabbit
Application WB, IHC, IHC (p)
Validations
  • (1)
Cat. No. ABIN6756666
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application WB, IHC
Validations
  • (2)
Cat. No. ABIN2788020
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
Application WB
Validations
  • (2)
Cat. No. ABIN2788021
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
Cat. No. ABIN7091801
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
Cat. No. ABIN7174285
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our USP2 抗体

Kitamura, Ishino, Shimamoto, Okabe, Miyamoto, Takahashi, Miyoshi: "Ubiquitin-Specific Protease 2 Modulates the Lipopolysaccharide-Elicited Expression of Proinflammatory Cytokines in Macrophage-like HL-60 Cells." in: Mediators of inflammation, Vol. 2017, pp. 6909415, (2018) (PubMed).

Ren, Zhao, Liu, Yuan, Cheng, Zuo, Qian, Liu, Guo, Zhang, Wang, Qian, Li, Ge, Dai, Xiong, Zheng: "Deubiquitinase USP2a Sustains Interferons Antiviral Activity by Restricting Ubiquitination of Activated STAT1 in the Nucleus." in: PLoS pathogens, Vol. 12, Issue 7, pp. e1005764, (2017) (PubMed).

Davis, Pragani, Fox, Shen, Parmar, Gaudiano, Liu, Tanega, McGee, Hall, McKnight, Shinn, Nelson, Chattopadhyay, DAndrea, Auld, DeLucas, Li, Boxer, Simeonov: "Small Molecule Inhibition of the Ubiquitin-specific Protease USP2 Accelerates cyclin D1 Degradation and Leads to Cell Cycle Arrest in Colorectal Cancer and Mantle Cell Lymphoma Models." in: The Journal of biological chemistry, Vol. 291, Issue 47, pp. 24628-24640, (2017) (PubMed).

Boustani, Khoshnood, Nikpasand, Taleshi, Ahmadi, Yahaghi, Goudarzi: "Overexpression of ubiquitin-specific protease 2a (USP2a) and nuclear factor erythroid 2-related factor 2 (Nrf2) in human gliomas." in: Journal of the neurological sciences, Vol. 363, pp. 249-52, (2016) (PubMed).

Zhang, Zhao, Zhang, Zhao, Gao: "Ubiquitin-specific protease 2b negatively regulates IFN-? production and antiviral activity by targeting TANK-binding kinase 1." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 193, Issue 5, pp. 2230-7, (2014) (PubMed).

Kitamura, Kimura, Shimamoto, Okabe, Ito, Miyamoto, Naoe, Kikuguchi, Meek, Toda, Okamoto, Kanehira, Hase, Watarai, Ishizuka, El-Osta, Ohara, Miyoshi: "Ubiquitin-specific protease 2-69 in macrophages potentially modulates metainflammation." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 27, Issue 12, pp. 4940-53, (2013) (PubMed).

Tong, Buelow, Guha, Rausch, Yin: "USP2a protein deubiquitinates and stabilizes the circadian protein CRY1 in response to inflammatory signals." in: The Journal of biological chemistry, Vol. 287, Issue 30, pp. 25280-91, (2012) (PubMed).

Alonso, Magyar, Wang, Bisello, Friedman: "Ubiquitination-deubiquitination balance dictates ligand-stimulated PTHR sorting." in: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Vol. 26, Issue 12, pp. 2923-34, (2011) (PubMed).

Bedard, Yang, Gregory, Cyr, Suzuki, Yu, Chian, Hermo, OFlaherty, Smith, Clarke, Wing: "Mice lacking the USP2 deubiquitinating enzyme have severe male subfertility associated with defects in fertilization and sperm motility." in: Biology of reproduction, Vol. 85, Issue 3, pp. 594-604, (2011) (PubMed).

Oberfeld, Ruffieux-Daidié, Vitagliano, Pos, Verrey, Staub: "Ubiquitin-specific protease 2-45 (Usp2-45) binds to epithelial Na+ channel (ENaC)-ubiquitylating enzyme Nedd4-2." in: American journal of physiology. Renal physiology, Vol. 301, Issue 1, pp. F189-96, (2011) (PubMed).

Aliases for USP2 抗体

ubiquitin specific peptidase 2 (USP2) 抗体
ubiquitin specific peptidase 2 (Usp2) 抗体
ubiquitin specific peptidase 2a (usp2a) 抗体
B930035K21Rik 抗体
UBP-t 抗体
UBP41 抗体
Ubp41 抗体
UBP46 抗体
ubp52 抗体
ubp66 抗体
USP9 抗体
zgc:92134 抗体
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