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USP19 产品

(Ubiquitin Specific Peptidase 19 (USP19))

Categories

  • USP19 抗体
Deubiquitinating enzyme that regulates the degradation of various proteins. Deubiquitinates and prevents proteasomal degradation of RNF123 which in turn stimulates CDKN1B ubiquitin- dependent degradation thereby playing a role in cell proliferation. Involved in decreased protein synthesis in atrophying skeletal muscle. Modulates transcription of major myofibrillar proteins. Also involved in turnover of endoplasmic- reticulum-associated degradation (ERAD) substrates. Regulates the stability of BIRC2/c-IAP1 and BIRC3/c-IAP2 by preventing their ubiquitination. Required for cells to mount an appropriate response to hypoxia and rescues HIF1A from degradation in a non- catalytic manner. Plays an important role in 17 beta-estradiol (E2)-inhibited myogenesis. Decreases the levels of ubiquitinated proteins during skeletal muscle formation and acts to repress myogenesis.

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Featured USP19 Categories

USP19 抗体

High quality antibodies with extensive validation data.

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Cat. No. ABIN7271147
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Reactivity Human
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Recommended USP19 蛋白

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Latest Publications for our USP19 Products

Altun, Zhao, Velasco, Liu, Hassink, Paschke, Pereira, Lindsten: "Ubiquitin-specific protease 19 (USP19) regulates hypoxia-inducible factor 1α (HIF-1α) during hypoxia." in: The Journal of biological chemistry, Vol. 287, Issue 3, pp. 1962-9, (2012) (PubMed).

Mei, Hahn, Hu, Yang: "The USP19 deubiquitinase regulates the stability of c-IAP1 and c-IAP2." in: The Journal of biological chemistry, Vol. 286, Issue 41, pp. 35380-7, (2011) (PubMed).

Hassink, Zhao, Sompallae, Altun, Gastaldello, Zinin, Masucci, Lindsten: "The ER-resident ubiquitin-specific protease 19 participates in the UPR and rescues ERAD substrates." in: EMBO reports, Vol. 10, Issue 7, pp. 755-61, (2009) (PubMed).

Zhu, Ménard, Sulea: "High incidence of ubiquitin-like domains in human ubiquitin-specific proteases." in: Proteins, Vol. 69, Issue 1, pp. 1-7, (2007) (PubMed).

Synonyms and alternative names related to USP19

ubiquitin specific peptidase 19 (usp19), ubiquitin specific peptidase 19 (USP19), universal stress protein (RR_RS18085), ubiquitin carboxyl-terminal hydrolase 19 (PTRG_09611), ubiquitin specific peptidase 19 (Usp19), 8430421I07Rik, AI047774, MGC145127, si:dkey-32e6.9, USP19, wu:fc26a05, ZMYND9, Zmynd9

Protein level used designations for USP19

  • ubiquitin specific peptidase 19
  • ubiquitin-specific protease 19
  • ubiquitin specific protease 19
  • universal stress protein
  • ubiquitin carboxyl-terminal hydrolase 19
  • ubiquitin carboxyl-terminal hydrolase 19-like
  • deubiquitinating enzyme 19
  • ubiquitin thioesterase 19
  • ubiquitin thiolesterase 19
  • ubiquitin-specific-processing protease 19
  • zinc finger MYND domain-containing protein 9
  • ubiquitin-specific processing protease 19
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