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USP17L2 产品

(Ubiquitin Specific Peptidase 17-Like 2 (USP17L2))

Categories

Deubiquitinating enzyme that specifically removes conjugated ubiquitin from CDC25A, thereby playing a key role in cell cycle regulation. Deubiquitination of CDC25A prevents its degradation by the proteasome during the G1/S and G2/M phases of the cell cycle and is required for cell-cycle progression. Has transforming capabilities on cell lines. May also function in cell apoptosis.

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Featured USP17L2 Categories

USP17L2 抗体

High quality antibodies with extensive validation data.

USP17L2 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended USP17L2 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN567050
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN567049
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN6745383
Quantity 100 μL
Datasheet Datasheet

Recommended USP17L2 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1352077
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3096106
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our USP17L2 Products

Fukuura, Inoue, Miyajima, Watanabe, Tokugawa, Morishita, Ohoka, Komada, Hayashi: "The ubiquitin-specific protease USP17 prevents cellular senescence by stabilizing the methyltransferase SET8 and transcriptionally repressing p21." in: The Journal of biological chemistry, Vol. 294, Issue 44, pp. 16429-16439, (2019) (PubMed).

McFarlane, Kelvin, de la Vega, Govender, Scott, Burrows, Johnston: "The deubiquitinating enzyme USP17 is highly expressed in tumor biopsies, is cell cycle regulated, and is required for G1-S progression." in: Cancer research, Vol. 70, Issue 8, pp. 3329-39, (2010) (PubMed).

Synonyms and alternative names related to USP17L2

ubiquitin specific peptidase 17-like family member 2 (USP17L2), ubiquitin carboxyl-terminal hydrolase 17 (LOC695235), DUB-3, DUB3, USP17

Protein level used designations for USP17L2

  • deubiquitinating enzyme 17-like protein 2
  • deubiquitinating enzyme 3
  • deubiquitinating protein 3
  • ubiquitin carboxyl-terminal hydrolase 17
  • ubiquitin carboxyl-terminal hydrolase 17-like protein 2
  • ubiquitin specific peptidase 17-like 2
  • ubiquitin thioesterase 17-like protein 2
  • ubiquitin thiolesterase 17-like protein 2
  • ubiquitin-specific-processing protease 17-like protein 2
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