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USP13 蛋白

(Ubiquitin Specific Peptidase 13 (Isopeptidase T-3) (USP13))

Deubiquitinase that mediates deubiquitination of target proteins such as BECN1, MITF, SKP2 and USP10 and is involved in various processes such as autophagy and endoplasmic reticulum- associated degradation (ERAD). Component of a regulatory loop that of BECN1, a key regulator of autophagy, leading to stabilize the PIK3C3/VPS34-containing complexes. Also deubiquitinates USP10, an essential regulator of p53/TP53 stability. In turn, PIK3C3/VPS34- containing complexes regulate USP13 stability, suggesting the existence of a regulatory system by which PIK3C3/VPS34-containing complexes regulate p53/TP53 protein levels via USP10 and USP13. Recruited by nuclear UFD1 and mediates deubiquitination of SKP2, thereby regulating endoplasmic reticulum-associated degradation (ERAD). Mediates stabilization of SIAH2 independently of impairing SIAH2 autoubiquitination. Has a weak deubiquitinase activity in vitro and preferentially cleaves 'Lys-63'-linked polyubiquitin chains. In contrast to USP5, it is not able to mediate unanchored polyubiquitin disassembly. Able to cleave ISG15 in vitro\; however, additional experiments are required to confirm such data (By similarity).

recommended

USP13 Protein (AA 1-863) (GST tag) (ABIN1324750)

USP13 宿主: 人宿主: 小麦胚 Recombinant ELISA, WB, AA, AP

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recommended

USP13 Protein (AA 1-863) (Strep Tag) (ABIN3096193)

USP13 宿主: 人宿主: Tobacco (Nicotiana tabacum) Recombinant > 80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, WB, SDS

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recommended

USP13 Protein (Myc-DYKDDDDK Tag) (ABIN2712394)

USP13 宿主: 人宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD

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USP13 蛋白 by Origin

Find USP13 蛋白 for a variety of species such as anti-Human USP13. The species listed below are among those available. Click on a link to go to the corresponding products.

USP13 蛋白 by Source

Here you will find USP13 蛋白 proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

USP13 蛋白 by 蛋白类型

Here you can find USP13 蛋白 proteins categorized by available protein types. Additional protein types can be located using our search function.

USP13 蛋白 by 应用范围

Find USP13 蛋白 validated for a specific application such as ELISA, WB, AP, AA. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular USP13 蛋白

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

USP13 Protein (AA 1-863) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1324750

Quantity 10 μg

Datasheet Datasheet

USP13 Protein (AA 1-863) (Strep Tag)

Reactivity Human

Source Tobacco (Nicotiana tabacum)

Validations

Cat. No. ABIN3096193

Quantity 1 mg

Datasheet Datasheet

USP13 Protein (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2712394

Quantity 20 μg

Datasheet Datasheet

Aliases for USP13 蛋白

ubiquitin specific peptidase 13 (USP13) 蛋白
ubiquitin specific peptidase 13 (isopeptidase T-3) (Usp13) 蛋白
ubiquitin specific peptidase 13 (isopeptidase T-3) (USP13) 蛋白
ubiquitin specific peptidase 13 (usp13) 蛋白
ubiquitin specific peptidase 13 (isopeptidase T-3) (usp13) 蛋白
ubiquitin carboxyl-terminal hydrolase 13 (MGYG_01656) 蛋白
universal stress protein (RR_RS02895) 蛋白
2700071E21Rik 蛋白
AI848077 蛋白
IsoT-3 蛋白
ISOT3 蛋白
MGC163140 蛋白
usp13 蛋白

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USP13 蛋白 by Origin

USP13 蛋白 by Source

USP13 蛋白 by 蛋白类型

USP13 蛋白 by 应用范围

Popular USP13 蛋白

Aliases for USP13 蛋白

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