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UPF3B 蛋白

(UPF3 Regulator of Nonsense Transcripts Homolog B (UPF3B))

This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. The encoded protein is one of two functional homologs to yeast Upf3p. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein. It forms with Y14 a complex that binds specifically 20 nt upstream of exon-exon junctions. This gene is located on the long arm of chromosome X. Two splice variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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UPF3B Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag) (ABIN2735037)

UPF3B 宿主: 人宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD

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Popular UPF3B 蛋白

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

UPF3B Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2735037

Quantity 20 μg

Datasheet Datasheet

Aliases for UPF3B 蛋白

UPF3B, regulator of nonsense mediated mRNA decay (UPF3B) 蛋白
UPF3 regulator of nonsense transcripts homolog B (yeast) (Upf3b) 蛋白
UPF3B, regulator of nonsense mediated mRNA decay (Upf3b) 蛋白
5730594O13Rik 蛋白
AI317193 蛋白
AW541158 蛋白
HUPF3B 蛋白
MRXS14 蛋白
RENT3B 蛋白
RGD1560264 蛋白
UPF3X 蛋白

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