ULK2 产品
(Unc-51 Like Kinase 2 (ULK2))
Categories
This gene encodes a protein that is similar to a serine/threonine kinase in C. elegans which is involved in axonal elongation. The structure of this protein is similar to the C. elegans protein in that both proteins have an N-terminal kinase domain, a central proline/serine rich (PS) domain, and a C-terminal (C) domain. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Dec 2008].
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Featured ULK2 Categories
Recommended ULK2 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC (p), IF, ICC
Validations
- (1)
- (5)
Cat. No.
ABIN2856810
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, FACS
Validations
- (5)
Cat. No.
ABIN5542414
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (3)
Cat. No.
ABIN7169209
Quantity
100 μg
Datasheet
Datasheet
Recommended ULK2 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1324623
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
Cat. No.
ABIN5509192
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3096205
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our ULK2 Products
: "TBC1D9 regulates TBK1 activation through Ca2+ signaling in selective autophagy." in: Nature communications, Vol. 11, Issue 1, pp. 770, (2020) (PubMed).: "Function of inhibitor of Bruton's tyrosine kinase isoform α (IBTKα) in nonalcoholic steatohepatitis links autophagy and the unfolded protein response." in: The Journal of biological chemistry, Vol. 292, Issue 34, pp. 14050-14065, (2017) (PubMed).
: "Transcriptional control of autophagy-lysosome function drives pancreatic cancer metabolism." in: Nature, Vol. 524, Issue 7565, pp. 361-5, (2015) (PubMed).
: "Methylation silencing of ULK2, an autophagy gene, is essential for astrocyte transformation and tumor growth." in: The Journal of biological chemistry, Vol. 289, Issue 32, pp. 22306-18, (2014) (PubMed).
: "ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery." in: Molecular biology of the cell, Vol. 20, Issue 7, pp. 1992-2003, (2009) (PubMed).
: "A human protein-protein interaction network: a resource for annotating the proteome. ..." in: Cell, Vol. 122, Issue 6, pp. 957-68, (2005) (PubMed).
: "Mouse ULK2, a novel member of the UNC-51-like protein kinases: unique features of functional domains." in: Oncogene, Vol. 18, Issue 43, pp. 5850-9, (1999) (PubMed).
: "Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts." in: Cell, Vol. 89, Issue 5, pp. 755-64, (1997) (PubMed).
Synonyms and alternative names related to ULK2
unc-51 like autophagy activating kinase 2 (ULK2), unc-51 like autophagy activating kinase 2 (Ulk2), unc-51 like kinase 2 (Ulk2), unc-51 like autophagy activating kinase 2 (ulk2), A830085I22Rik, ATG1B, AU015340, mKIAA0623, ULK2, Unc51.2Protein level used designations for ULK2
- unc-51-like kinase 2 (C. elegans)
- serine/threonine-protein kinase ULK2
- Unc-51 like kinase 2
- serine/threonine-protein kinase Unc51.2
- unc-51-like kinase 2
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