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UIMC1 蛋白

(Ubiquitin Interaction Motif Containing 1 (UIMC1))
Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Plays a central role in the BRCA1-A complex by specifically binding 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). The BRCA1-A complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX. Also weakly binds monoubiquitin but with much less affinity than 'Lys-63'-linked ubiquitin. May interact with monoubiquitinated histones H2A and H2B\; the relevance of such results is however unclear in vivo. Does not bind Lys-48'-linked ubiquitin. May indirectly Act as a transcriptional repressor by inhibiting the interaction of NR6A1 with the corepressor NCOR1 (By similarity).
UIMC1 Protein (AA 1-385) (GST tag) UIMC1 Protein (AA 1-385) (GST tag) UIMC1 Protein (AA 1-385) (GST tag) (ABIN1324614)

UIMC1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP

UIMC1 Protein (AA 1-719) (Strep Tag) (ABIN3096257)

UIMC1 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant > 80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, WB, SDS

UIMC1 Protein (AA 1-726) (His tag) (ABIN1634738)

UIMC1 宿主: 大鼠 宿主: 酵母菌 Recombinant > 90 % ELISA

UIMC1 蛋白 by Origin

Find UIMC1 蛋白 for a variety of species such as anti-Human UIMC1, anti-Rat UIMC1. The species listed below are among those available. Click on a link to go to the corresponding products.

UIMC1 蛋白 by Source

Here you will find UIMC1 蛋白 proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

UIMC1 蛋白 by 蛋白类型

Here you can find UIMC1 蛋白 proteins categorized by available protein types. Additional protein types can be located using our search function.

UIMC1 蛋白 by 应用范围

Find UIMC1 蛋白 validated for a specific application such as ELISA, WB, AP, AA. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular UIMC1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1324614
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3096257
Quantity 1 mg
Datasheet Datasheet
Reactivity Rat
Source Yeast
Validations
Cat. No. ABIN1634738
Quantity 1 mg
Datasheet Datasheet

Aliases for UIMC1 蛋白

ubiquitin interaction motif containing 1 (UIMC1) 蛋白
ubiquitin interaction motif containing 1 (Uimc1) 蛋白
9430016E08Rik 蛋白
D330018D10Rik 蛋白
D630032M02Rik 蛋白
RAP80 蛋白
RGD1307009 蛋白
RIP110 蛋白
Rxrip110 蛋白
UIMC1 蛋白
X2HRIP110 蛋白
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