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UGT2B4 产品

(UDP Glucuronosyltransferase 2 Family, Polypeptide B4 (UGT2B4))

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UDPGTs are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isozyme is active on polyhydroxylated estrogens (such as estriol, 4-hydroxyestrone and 2-hydroxyestriol) and xenobiotics (such as 4-methylumbelliferone, 1-naphthol, 4- nitrophenol, 2-aminophenol, 4-hydroxybiphenyl and menthol). It is capable of 6 alpha-hydroxyglucuronidation of hyodeoxycholic acid.

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Featured UGT2B4 Categories

UGT2B4 抗体

High quality antibodies with extensive validation data.

Recommended UGT2B4 抗体

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Reactivity Human
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Cat. No. ABIN6242687
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Cat. No. ABIN1881977
Quantity 400 μL
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Cat. No. ABIN521246
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Recommended UGT2B4 蛋白

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Datasheet Datasheet

Latest Publications for our UGT2B4 Products

Lévesque, Ménard, Laverdière, Bellemare, Barbier, Girard, Guillemette: "Extensive splicing of transcripts encoding the bile acid-conjugating enzyme UGT2B4 modulates glucuronidation." in: Pharmacogenetics and genomics, Vol. 20, Issue 3, pp. 195-210, (2010) (PubMed).

Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, (2010) (PubMed).

Yong, Schwartz, Atkinson, Makar, Thomas, Newton, Aiello Bowles, Holt, Leisenring, Lampe: "Associations between polymorphisms in glucuronidation and sulfation enzymes and mammographic breast density in premenopausal women in the United States." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 19, Issue 2, pp. 537-46, (2010) (PubMed).

Synonyms and alternative names related to UGT2B4

UDP glucuronosyltransferase family 2 member B4 (UGT2B4), UDP-glucuronosyltransferase 2B4 (LOC615303), UDP-glucuronosyltransferase 2B4 (LOC100066359), HLUG25, UDPGT2B4, UDPGTH1, UGT2B11, UGT2B17, UGT2B28

Protein level used designations for UGT2B4

  • UDP glucuronosyltransferase 2B4
  • UDP-glucuronosyltransferase 2B4
  • UDP-glucuronyltransferase, family 2, beta-4
  • UDPGT 2B4
  • UDPGTh-1
  • hyodeoxycholic acid
  • hyodeoxycholic acid-specific UDPGT
  • UDP glucuronosyltransferase 2 family, polypeptide B17
  • UDP glycosyltransferase 2 family, polypeptide B28
  • UDP glucuronosyltransferase 2 family, polypeptide B4
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