UGT1A9 产品
(UDP Glucuronosyltransferase 1 Family, Polypeptide A9 (UGT1A9))
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This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene is active on phenols. [provided by RefSeq, Jul 2008].
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Recommended UGT1A9 抗体
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Reactivity
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Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (2)
- (3)
Cat. No.
ABIN527130
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC
Validations
- (4)
Cat. No.
ABIN3022343
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
IF, IHC, ELISA
Validations
- (3)
Cat. No.
ABIN7174631
Quantity
100 μg
Datasheet
Datasheet
Recommended UGT1A9 蛋白
Latest Publications for our UGT1A9 Products
: "Association analysis of UGT1A genotype and haplotype with SN-38 glucuronidation in human livers." in: Pharmacogenomics, Vol. 15, Issue 6, pp. 785-98, (2014) (PubMed).: "Altered UDP-glucuronosyltransferase and sulfotransferase expression and function during progressive stages of human nonalcoholic fatty liver disease." in: Drug metabolism and disposition: the biological fate of chemicals, Vol. 41, Issue 3, pp. 554-61, (2013) (PubMed).
: "Preparation of a specific monoclonal antibody against human UDP-glucuronosyltransferase (UGT) 1A9 and evaluation of UGT1A9 protein levels in human tissues." in: Drug metabolism and disposition: the biological fate of chemicals, Vol. 40, Issue 8, pp. 1620-7, (2012) (PubMed).
: "Quantitative analysis of UDP-glucuronosyltransferase (UGT) 1A and UGT2B expression levels in human livers." in: Drug metabolism and disposition: the biological fate of chemicals, Vol. 37, Issue 8, pp. 1759-68, (2009) (PubMed).
Synonyms and alternative names related to UGT1A9
UDP glycosyltransferase 1 family, polypeptide A9 (UGT1A9), UDP glucuronosyltransferase 1 family, polypeptide A9 (UGT1A9), UDP glucuronosyltransferase family 1 member A9 (UGT1A9), UDP glucuronosyltransferase 1 family, polypeptide A9 (Ugt1a9), UDP glucuronosyltransferase family 1 member A9 (Ugt1a9), DKFZP469N0814, HLUGP4, LUGP4, mUGTBr/P, SHEUGT1A07, UDPGT, UDPGT 1-9, UGT-1I, UGT1-09, UGT1-9, UGT1.9, UGT1A9, Ugt1a10, Ugt1a11, Ugt1a12, UGT1AI, UGT1I, UGTP4Protein level used designations for UGT1A9
- UDP glycosyltransferase 1 family, polypeptide A9
- UDP-glucuronosyltransferase 1-9
- UDP-glucuronosyltransferase 1A9
- UDP glucuronosyltransferase 1 family, polypeptide A9
- UDP glycosyl transferase 1A9
- UDP-glucuronosyltransferase 1-I
- UDP glycosyltransferase 1 family polypeptide A12
- UDP-glucuronosyltransferase 1-7
- UDP glycosyltransferase 1 family polypeptide A10
- UDP glycosyltransferase 1 family polypeptide A11
- UDP glycosyltransferase 1 family, polypeptide A10
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