UGT1A8 Protein (Myc-DYKDDDDK Tag)
UGT1A8
宿主: 人
宿主: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
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- 抗原
- UGT1A8 (UDP Glucuronosyltransferase 1 Family, Polypeptide A8 (UGT1A8))
- 蛋白类型
- Recombinant
- 宿主
- 人
- 资源
- HEK-293 Cells
- 标记
- This UGT1A8 protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human UDP glucuronosyltransferase 1 family, polypeptide A8 (UGT1A8) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- UGT1A8 (UDP Glucuronosyltransferase 1 Family, Polypeptide A8 (UGT1A8))
- 别名
- UDPGT Protein, UDPGT 1-8 Protein, UGT-1H Protein, UGT1-08 Protein, UGT1.8 Protein, UGT1A8S Protein, UGT1H Protein, A116 Protein, OTTMUSG00000020811 Protein, Ugt1 Protein, Ugt1a9 Protein, UDP glucuronosyltransferase 1 family, polypeptide A8 Protein, UDP glucuronosyltransferase family 1 member A8 Protein, UDP glycosyltransferase 1 family, polypeptide A8 Protein, UGT1A8 Protein, Ugt1a8 Protein
- 背景
- This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5&apos exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene has glucuronidase activity with many substrates including coumarins, phenols, anthraquinones, flavones, and some opioids.
- 分子量
- 57.1 kDa
- NCBI登录号
- NP_061949
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