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UGT1A4 产品

(UDP Glucuronosyltransferase 1 Family, Polypeptide A4 (UGT1A4))

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This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. This enzyme has some glucuronidase activity towards bilirubin, although is is more active on amines, steroids, and sapogenins. [provided by RefSeq, Jul 2008].

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Featured UGT1A4 Categories

UGT1A4 抗体

High quality antibodies with extensive validation data.

UGT1A4 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

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Recommended UGT1A4 蛋白

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Synonyms and alternative names related to UGT1A4

UDP glucuronosyltransferase family 1 member A4 (UGT1A4), UDP-glucuronosyltransferase 1-4 (UGT1-4), HUG-BR2, UDPGT, UDPGT 1-4, UGT-1D, UGT1, UGT1-04, UGT1.4, UGT1A4, UGT1D

Protein level used designations for UGT1A4

  • UDP glycosyltransferase 1 family, polypeptide A4
  • UDP-glucuronosyltransferase 1-4
  • UDP-glucuronosyltransferase 1-D
  • UDP-glucuronosyltransferase 1A4
  • bilirubin UDP-glucuronosyltransferase isozyme 2
  • bilirubin-specific UDPGT isozyme 2
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