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UCP3 产品

(Uncoupling Protein 3 (Mitochondrial, Proton Carrier) (UCP3))

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Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. The different UCPs have tissue-specific expression\; this gene is primarily expressed in skeletal muscle. This gene's protein product is postulated to protect mitochondria against lipid-induced oxidative stress. Expression levels of this gene increase when fatty acid supplies to mitochondria exceed their oxidation capacity and the protein enables the export of fatty acids from mitochondria. UCPs contain the three solcar protein domains typically found in MACPs. Two splice variants have been found for this gene.[provided by RefSeq, Nov 2008].

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Featured UCP3 Categories

UCP3 抗体

High quality antibodies with extensive validation data.

UCP3 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

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Latest Publications for our UCP3 Products

Tomilov, Bettaieb, Kim, Sahdeo, Tomilova, Lam, Hagopian, Connell, Fong, Rowland, Griffey, Ramsey, Haj, Cortopassi: "Shc depletion stimulates brown fat activity in vivo and in vitro." in: Aging cell, Vol. 13, Issue 6, pp. 1049-58, (2014) (PubMed).

Mayrhofer, Krieger, Huttary, Chang, Grillari, Allmaier, Kerjaschki: "Alterations in fatty acid utilization and an impaired antioxidant defense mechanism are early events in podocyte injury: a proteomic analysis." in: The American journal of pathology, Vol. 174, Issue 4, pp. 1191-202, (2009) (PubMed).

Synonyms and alternative names related to UCP3

uncoupling protein 3 (UCP3), uncoupling protein (UCP3), uncoupling protein (UCP1), uncoupling protein (UCP2), mitochondrial uncoupling protein 3 (LOC100303663), uncoupling protein 3 (mitochondrial, proton carrier) S homeolog (ucp3.S), mitochondrial uncoupling protein 3 (LOC100229080), uncoupling protein 3 (mitochondrial, proton carrier) (Ucp3), uncoupling protein 3 (Ucp3), AI645527, LOC100229080, slc25a9, SLC25A9, Slc25a9, UCP, UCP-3, UCP3

Protein level used designations for UCP3

  • mitochondrial carrier
  • mitochondrial uncoupling protein
  • mitochondrial uncoupling protein 3
  • uncoupling protein
  • uncoupling protein 3 (mitochondrial, proton carrier)
  • uncoupling protein UCP
  • mitochondrial uncoupling protein 3-like
  • solute carrier family 25 member 9
  • UCP 3
  • uncoupling protein 3, mitochondrial
  • Uncoupling protein 3, mitochondrial
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