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Ubiquitin-Conjugating Enzyme E2K 产品

(Ubiquitin-Conjugating Enzyme E2K (UBE2K))
The protein encoded by this gene belongs to the ubiquitin-conjugating enzyme family. This protein interacts with RING finger proteins, and it can ubiquitinate huntingtin, the gene product for Huntington's disease. Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases, a role in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and involvement in foam cell formation. Multiple transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008].

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Featured Ubiquitin-Conjugating Enzyme E2K Categories

Ubiquitin-Conjugating Enzyme E2K 抗体

High quality antibodies with extensive validation data.

Ubiquitin-Conjugating Enzyme E2K ELISA试剂盒

Reliable ELISA kits for a wide range of species.

Ubiquitin-Conjugating Enzyme E2K 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Ubiquitin-Conjugating Enzyme E2K 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application WB, IF, IHC (p)
Validations
  • (3)
  • (3)
Cat. No. ABIN1882088
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (2)
Cat. No. ABIN7174460
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, WB
Validations
  • (2)
Cat. No. ABIN516450
Quantity 100 μg
Datasheet Datasheet

Recommended Ubiquitin-Conjugating Enzyme E2K ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6960356
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN5655204
Quantity 96 tests
Datasheet Datasheet

Recommended Ubiquitin-Conjugating Enzyme E2K 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7125621
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1324382
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN1097733
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our Ubiquitin-Conjugating Enzyme E2K Products

Loeffler, Smith, Coffey, Aasly, LeWitt: "CSF Nrf2 and HSPA8 in Parkinson's disease patients with and without LRRK2 gene mutations." in: Journal of neural transmission (Vienna, Austria : 1996), Vol. 123, Issue 3, pp. 179-87, (2016) (PubMed).

Fromm-Dornieden, von der Heyde, Lytovchenko, Salinas-Riester, Brenig, Beissbarth, Baumgartner: "Novel polysome messages and changes in translational activity appear after induction of adipogenesis in 3T3-L1 cells." in: BMC molecular biology, Vol. 13, pp. 9, (2012) (PubMed).

Bae, Kho, Lee, Rhim, Kang: "Hip2 interacts with and destabilizes Smac/DIABLO." in: Biochemical and biophysical research communications, Vol. 397, Issue 4, pp. 718-23, (2010) (PubMed).

de Pril, Fischer, Roos, van Leeuwen: "Ubiquitin-conjugating enzyme E2-25K increases aggregate formation and cell death in polyglutamine diseases." in: Molecular and cellular neurosciences, Vol. 34, Issue 1, pp. 10-9, (2007) (PubMed).

Christensen, Brzovic, Klevit: "E2-BRCA1 RING interactions dictate synthesis of mono- or specific polyubiquitin chain linkages." in: Nature structural & molecular biology, Vol. 14, Issue 10, pp. 941-8, (2007) (PubMed).

Flierman, Coleman, Pickart, Rapoport, Chau: "E2-25K mediates US11-triggered retro-translocation of MHC class I heavy chains in a permeabilized cell system." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 31, pp. 11589-94, (2006) (PubMed).

Yamada, Ohnishi, Ohkawara, Iemura, Satoh, Hyodo-Miura, Kawachi, Natsume, Shibuya: "NARF, an nemo-like kinase (NLK)-associated ring finger protein regulates the ubiquitylation and degradation of T cell factor/lymphoid enhancer factor (TCF/LEF)." in: The Journal of biological chemistry, Vol. 281, Issue 30, pp. 20749-60, (2006) (PubMed).

Furukawa, Kubo, Kikuchi, Tokura, Fujita, Sakurabayashi: "Regulation of macrophage-specific gene expression by degenerated lipoproteins." in: Electrophoresis, Vol. 21, Issue 2, pp. 338-46, (2000) (PubMed).

Kikuchi, Furukawa, Kubo, Tokura, Hayashi, Nakamura, Matsuda, Sakurabayashi: "Induction of ubiquitin-conjugating enzyme by aggregated low density lipoprotein in human macrophages and its implications for atherosclerosis." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 20, Issue 1, pp. 128-34, (2000) (PubMed).

Petersén, Mani, Brundin: "Recent advances on the pathogenesis of Huntington's disease." in: Experimental neurology, Vol. 157, Issue 1, pp. 1-18, (1999) (PubMed).

Synonyms and alternative names related to Ubiquitin-Conjugating Enzyme E2K

ubiquitin conjugating enzyme E2 K (UBE2K), ubiquitin-conjugating enzyme E2K (Ube2k), ubiquitin conjugating enzyme E2 K S homeolog (ube2k.S), ubiquitin conjugating enzyme E2 K (ube2k), ubiquitin-conjugating enzyme E2Kb (UBC1 homolog, yeast) (ube2kb), ubiquitin conjugating enzyme E2 K (Ube2k), ubiquitin-conjugating enzyme E2Ka (UBC1 homolog, yeast) (ube2ka), AW492011, D5Ertd601e, E2-25K, E2-25k, e2-25k, HIP2, Hip2, hip2, HYPG, Hypg, hypg, LIG, Lig, lig, UBC1, ube2k, zgc:103472, zgc:110791

Protein level used designations for Ubiquitin-Conjugating Enzyme E2K

  • E2(25K)
  • HIP-2
  • huntingtin interacting protein 2
  • huntingtin-interacting protein 2
  • ubiquitin carrier protein
  • ubiquitin-conjugating enzyme E2 K
  • ubiquitin-conjugating enzyme E2(25K)
  • ubiquitin-conjugating enzyme E2-25 KDA
  • ubiquitin-conjugating enzyme E2-25K
  • ubiquitin-conjugating enzyme E2K (UBC1 homolog, yeast)
  • ubiquitin-protein ligase
  • ubiquitin-conjugating enzyme E2-25 kDa
  • ubiquitin-conjugating enzyme E2K (UBC1 homolog)
  • huntingtin interacting protein 2-like protein
  • ubiquitin-conjugating enzyme E2 K-like
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