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Ubiquitin 产品

(Ubiquitin)
Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys in protein degradation via the proteasome. Linear polymer chains formed via attachment by the initiator Met lead to cell signaling. Ubiquitin is usually conjugated to Lys residues of target proteins, however, in rare cases, conjugation to Cys or Ser residues has been observed. When polyubiquitin is free (unanchored-polyubiquitin), it also has distinct roles, such as in activation of protein kinases, and in signaling (By similarity).

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Featured Ubiquitin Categories

Ubiquitin 抗体

High quality antibodies with extensive validation data.

Ubiquitin ELISA试剂盒

Reliable ELISA kits for a wide range of species.

Ubiquitin 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Ubiquitin 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Cow
Application WB, IHC, IF, ICC, IP
Validations
  • (2)
  • (6)
Cat. No. ABIN361831
Quantity 200 μL
Datasheet Datasheet
Reactivity Cow, Dog, Horse, Human, Mouse, Pig, Rabbit, Rat
Application WB, IHC, ICC, IP
Validations
  • (7)
Cat. No. ABIN7443803
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Rat
Application WB, IHC, ICC, IP
Validations
  • (9)
Cat. No. ABIN7428593
Quantity 100 μL
Datasheet Datasheet

Recommended Ubiquitin ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6962238
Quantity 96 tests
Datasheet Datasheet
Reactivity Cow, Dog, Horse, Human, Mouse, Pig, Rabbit, Rat
Analytical Method Quantitative Competition ELISA
Validations
  • (1)
Cat. No. ABIN6960339
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN1030104
Quantity 96 tests
Datasheet Datasheet

Recommended Ubiquitin 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7125573
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN934908
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7505806
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our Ubiquitin Products

Aubi, Prestegård, Jung-Kc, Shi, Ying, Grindheim, Scherer, Ulvik, McCann, Spriet, Thöny, Martinez: "The Pah-R261Q mouse reveals oxidative stress associated with amyloid-like hepatic aggregation of mutant phenylalanine hydroxylase." in: Nature communications, Vol. 12, Issue 1, pp. 2073, (2021) (PubMed).

Ji, Yao, Zhao, Zhai, Weng, He: "Extracellular ubiquitin levels are increased in coronary heart disease and associated with the severity of the disease." in: Scandinavian journal of clinical and laboratory investigation, Vol. 80, Issue 3, pp. 256-264, (2020) (PubMed).

Aalto, Mohan, Schwintzer, Kupka, Kietz, Walczak, Broemer, Meinander: "M1-linked ubiquitination by LUBEL is required for inflammatory responses to oral infection in Drosophila." in: Cell death and differentiation, Vol. 26, Issue 5, pp. 860-876, (2019) (PubMed).

Gladkova, Maslen, Skehel, Komander: "Mechanism of parkin activation by PINK1." in: Nature, Vol. 559, Issue 7714, pp. 410-414, (2019) (PubMed).

Sn, Pandurangi, Murumalla, Dj, Garimella, Acharya, Rai, Paul, Yarreiphang, Pillai, Giridharan, Clement, Alladi, Saiyed, Manjithaya: "Small molecule modulator of aggrephagy regulates neuroinflammation to curb pathogenesis of neurodegeneration." in: EBioMedicine, Vol. 50, pp. 260-273, (2019) (PubMed).

Nombela, Requena-Platek, Morales-Lange, Chico, Puente-Marin, Ciordia, Mena, Coll, Perez, Mercado, Ortega-Villaizan: "Rainbow Trout Red Blood Cells Exposed to Viral Hemorrhagic Septicemia Virus Up-Regulate Antigen-Processing Mechanisms and MHC I&II, CD86, and CD83 Antigen-presenting Cell Markers." in: Cells, Vol. 8, Issue 5, (2019) (PubMed).

Gogoi, Ravikumar, Dixit, Chakravortty: "Salmonella escapes K63 ubiquitination mediated MHC II endosomal proteolysis via modulation of endosomal acidification in dendritic cells." in: Pathogens and disease, (2018) (PubMed).

Yang, Liu, Yao, Jiang, Wang, Yang, Sun, Miao, Wang, Huang, Wang, Tang, Rayner, Britt, McVoy, Luo, Zhao: "WDR5 Facilitates Human Cytomegalovirus Replication by Promoting Capsid Nuclear Egress." in: Journal of virology, Vol. 92, Issue 9, (2018) (PubMed).

Michel, Swatek, Hospenthal, Komander: "Ubiquitin Linkage-Specific Affimers Reveal Insights into K6-Linked Ubiquitin Signaling." in: Molecular cell, Vol. 68, Issue 1, pp. 233-246.e5, (2017) (PubMed).

Gersch, Gladkova, Schubert, Michel, Maslen, Komander: "Mechanism and regulation of the Lys6-selective deubiquitinase USP30." in: Nature structural & molecular biology, Vol. 24, Issue 11, pp. 920-930, (2017) (PubMed).

Synonyms and alternative names related to Ubiquitin

Ubiquitin-63E (Ubi-p63E), Ubiquitin-5E (Ubi-p5E), transmembrane and ubiquitin-like domain containing 2 (tmub2), polyubiquitin (LOC100194618), Putative ubiquitin family protein (pco110026), ubiquitin (LOC100135798), ubiquitin B (UBB), UBiQuitin (ubq-1), Ubiquitin (LOC100190766), CG11624, CG18282, CG32744, CR32744, Dmel\\CG11624, Dmel\\CG32744, DmUb, DmUbi-p5E, DmUbi-p63E, LOC100194618, LOC100282068, si:busm1-180g5.5, si:dz180g5.5, Ub, ubi, Ubi-p, Ubi-P63e, ubi-p63E, Ubi63E, ubi63E, Ubi63p, Ubip, Ubiq, UBIQ, ubiquitin, Ubiquitin, Ubp

Protein level used designations for Ubiquitin

  • CG11624-PA
  • CG11624-PB
  • CG11624-PC
  • CG11624-PD
  • Ubi-p63E-PA
  • Ubi-p63E-PB
  • Ubi-p63E-PC
  • Ubi-p63E-PD
  • Ubiquitin-polymeric
  • polyubiquitin
  • ubiquitin
  • CG32744-PA
  • Ubi-p5E-PA
  • transmembrane and ubiquitin-like domain-containing protein 2
  • polyubiquitin containing 7 ubiquitin monomers
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