UBE3B 产品
(Ubiquitin Protein Ligase E3B (UBE3B))
Categories
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: E1 ubiquitin-activating enzymes, E2 ubiquitin-conjugating enzymes, and E3 ubiquitin-protein ligases. This gene encodes a member of the E3 ubiquitin-conjugating enzyme family which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme and transfers the ubiquitin to the targeted substrates. A HECT (homology to E6-AP C-terminus) domain in the C-terminus of the longer isoform of this protein is the catalytic site of ubiquitin transfer and forms a complex with E2 conjugases. Shorter isoforms of this protein which lack the C-terminal HECT domain are therefore unlikely to bind E2 enzymes. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2012].
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Featured UBE3B Categories
Recommended UBE3B 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, ICC, IF
Validations
- (3)
Cat. No.
ABIN6265855
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Bat, Chicken, Cow, Dog, Guinea Pig, Hamster, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat
Application
WB
Validations
- (1)
Cat. No.
ABIN6740821
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB
Validations
- (1)
Cat. No.
ABIN631147
Quantity
100 μL
Datasheet
Datasheet
Recommended UBE3B 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1324429
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
Cat. No.
ABIN1324428
Quantity
25 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3096166
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our UBE3B Products
: "Gene expression profile associated with postnatal development of pyramidal neurons in the human prefrontal cortex implicates ubiquitin ligase E3 in the pathophysiology of schizophrenia onset." in: Journal of psychiatric research, Vol. 102, pp. 110-117, (2019) (PubMed).: "Violating the splicing rules: TG dinucleotides function as alternative 3' splice sites in U2-dependent introns." in: Genome biology, Vol. 8, Issue 8, pp. R154, (2008) (PubMed).
Synonyms and alternative names related to UBE3B
ubiquitin protein ligase E3B (UBE3B), ubiquitin protein ligase E3B (ube3b), ubiquitin-protein ligase E3B (LOC581811), ubiquitin protein ligase E3B L homeolog (ube3b.L), ubiquitin protein ligase E3B (Ube3b), AI449831, AU020130, BPIDS, si:dkey-189p24.3Protein level used designations for UBE3B
- ubiquitin-protein ligase E3B
- ubiquitin protein ligase E3B
- ubiquitin-protein ligase E3B-like
- ubiquitin protein ligase E3
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