ube3a 抗体
(Ubiquitin Protein Ligase E3A (ube3a))
This gene encodes an E3 ubiquitin-protein ligase, part of the ubiquitin protein degradation system. This imprinted gene is maternally expressed in brain and biallelically expressed in other tissues. Maternally inherited deletion of this gene causes Angelman Syndrome, characterized by severe motor and intellectual retardation, ataxia, hypotonia, epilepsy, absence of speech, and characteristic facies. The protein also interacts with the E6 protein of human papillomavirus types 16 and 18, resulting in ubiquitination and proteolysis of tumor protein p53. Alternative splicing of this gene results in three transcript variants encoding three isoforms with different N-termini. Additional transcript variants have been described, but their full length nature has not been determined. [provided by RefSeq, Jul 2008].
recommended
ube3a 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 2F6 unconjugated
recommended
recommended
ube3a 适用: 人 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB4440 unconjugated
ube3a 抗体 by 抗体来源
Find ube3a 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.
ube3a 抗体 by 克隆形成能力
Find available monoclonal or polyclonal ube3a 抗体. Click on a link to go to the corresponding products.
ube3a 抗体 by 克隆
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Popular ube3a 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, IHC (p)
Validations
- (1)
- (6)
Cat. No.
ABIN563326
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
IHC, IF
Validations
- (11)
Cat. No.
ABIN7076105
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, IHC (p), FACS
Validations
- (1)
- (4)
Cat. No.
ABIN388925
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC
Validations
- (3)
Cat. No.
ABIN7259701
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC
Validations
- (3)
Cat. No.
ABIN6149835
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application
WB
Validations
- (4)
Cat. No.
ABIN2775648
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
IHC, ELISA, IF
Validations
- (2)
Cat. No.
ABIN7174571
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
IF, IHC (p), ICC
Validations
- (2)
Cat. No.
ABIN2854930
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF/ICC, FACS
Validations
- (3)
Cat. No.
ABIN3001484
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (1)
Cat. No.
ABIN7433114
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Bat, Chicken, Cow, Dog, Guinea Pig, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat, Zebrafish (Danio rerio)
Application
WB
Validations
- (1)
Cat. No.
ABIN6743133
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Bat, Drosophila melanogaster, Human, Monkey, Rat, Zebrafish (Danio rerio)
Application
WB
Validations
- (1)
Cat. No.
ABIN6743132
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
Cat. No.
ABIN633810
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Cow, Dog, Goat, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Saccharomyces cerevisiae, Zebrafish (Danio rerio)
Application
WB
Validations
- (2)
Cat. No.
ABIN2775647
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p), EIA
Validations
- (2)
Cat. No.
ABIN357571
Quantity
0.4 mL
Datasheet
Datasheet
Latest Publications for our ube3a 抗体
: "Cognition and Synaptic-Plasticity Related Changes in Aged Rats Supplemented with 8- and 10-Carbon Medium Chain Triglycerides." in: PLoS ONE, Vol. 11, Issue 8, pp. e0160159, (2017) (PubMed).: "A fine balance: Regulation of hippocampal Arc/Arg3.1 transcription, translation and degradation in a rat model of normal cognitive aging." in: Neurobiology of learning and memory, Vol. 115, pp. 58-67, (2014) (PubMed).
: "E6AP ubiquitin ligase regulates PML-induced senescence in Myc-driven lymphomagenesis." in: Blood, Vol. 120, Issue 4, pp. 822-32, (2012) (PubMed).
: "Ube3a-ATS is an atypical RNA polymerase II transcript that represses the paternal expression of Ube3a." in: Human molecular genetics, Vol. 21, Issue 13, pp. 3001-12, (2012) (PubMed).
: "Spatial and temporal silencing of the human maternal UBE3A gene." in: European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society, Vol. 16, Issue 6, pp. 587-91, (2012) (PubMed).
: "Adeno-associated virus-mediated rescue of the cognitive defects in a mouse model for Angelman syndrome." in: PLoS ONE, Vol. 6, Issue 12, pp. e27221, (2011) (PubMed).
: "Genomic imprinting of experience-dependent cortical plasticity by the ubiquitin ligase gene Ube3a." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 12, pp. 5611-6, (2010) (PubMed).
: "Isoform-specific degradation of PR-B by E6-AP is critical for normal mammary gland development." in: Molecular endocrinology (Baltimore, Md.), Vol. 24, Issue 11, pp. 2099-113, (2010) (PubMed).
: "E6 proteins from multiple human betapapillomavirus types degrade Bak and protect keratinocytes from apoptosis after UVB irradiation." in: Journal of virology, Vol. 82, Issue 21, pp. 10408-17, (2008) (PubMed).
: "Thiothymidine plus low-dose UVA kills hyperproliferative human skin cells independently of their human papilloma virus status." in: Molecular cancer therapeutics, Vol. 6, Issue 9, pp. 2487-95, (2007) (PubMed).
Aliases for ube3a 抗体
ubiquitin protein ligase E3A (UBE3A) 抗体ubiquitin-protein ligase E3A (ube3a) 抗体
ubiquitin-protein ligase E3A (LOC100194730) 抗体
ubiquitin protein ligase E3A (Ube3a) 抗体
ubiquitin protein ligase E3A (ube3a) 抗体
Ubiquitin protein ligase E3A (Ube3a) 抗体
ubiquitin protein ligase E3A (human papilloma virus E6-associated protein, Angelman syndrome) S homeolog (ube3a.S) 抗体
ubiquitin protein ligase E3A (human papilloma virus E6-associated protein, Angelman syndrome) (ube3a) 抗体
ubiquitin protein ligase E3A (Eint_040430) 抗体
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