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Tumor Necrosis Factor (Ligand) Superfamily, Member 11 蛋白

(Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11))
This gene encodes a member of the tumor necrosis factor (TNF) cytokine family which is a ligand for osteoprotegerin and functions as a key factor for osteoclast differentiation and activation. This protein was shown to be a dentritic cell survival factor and is involved in the regulation of T cell-dependent immune response. T cell activation was reported to induce expression of this gene and lead to an increase of osteoclastogenesis and bone loss. This protein was shown to activate antiapoptotic kinase AKT/PKB through a signaling complex involving SRC kinase and tumor necrosis factor receptor-associated factor (TRAF) 6, which indicated this protein may have a role in the regulation of cell apoptosis. Targeted disruption of the related gene in mice led to severe osteopetrosis and a lack of osteoclasts. The deficient mice exhibited defects in early differentiation of T and B lymphocytes, and failed to form lobulo-alveolar mammary structures during pregnancy. Two alternatively spliced transcript variants have been found. [provided by RefSeq, Jul 2008].
RANKL Protein (AA 63-244) (His-DYKDDDDK Tag) RANKL Protein (AA 63-244) (His-DYKDDDDK Tag) RANKL Protein (AA 63-244) (His-DYKDDDDK Tag) (ABIN7275517)

TNFSF11 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Tris-Bis PAGE

RANKL Protein (AA 63-244) RANKL Protein (AA 63-244) RANKL Protein (AA 63-244) (ABIN7275516)

TNFSF11 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Tris-Bis PAGE,> 90 % as determined by HPLC

RANKL Protein (AA 70-316) (His tag) RANKL Protein (AA 70-316) (His tag) RANKL Protein (AA 70-316) (His tag) (ABIN7275518)

TNFSF11 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Tumor Necrosis Factor (Ligand) Superfamily, Member 11 蛋白 by Origin

Find Tumor Necrosis Factor (Ligand) Superfamily, Member 11 蛋白 for a variety of species such as anti-Human Tumor Necrosis Factor (Ligand) Superfamily, Member 11, anti-Mouse Tumor Necrosis Factor (Ligand) Superfamily, Member 11, anti-Rat Tumor Necrosis Factor (Ligand) Superfamily, Member 11. The species listed below are among those available. Click on a link to go to the corresponding products.

Tumor Necrosis Factor (Ligand) Superfamily, Member 11 蛋白 by Source

Here you will find Tumor Necrosis Factor (Ligand) Superfamily, Member 11 蛋白 proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

Tumor Necrosis Factor (Ligand) Superfamily, Member 11 蛋白 by 蛋白类型

Here you can find Tumor Necrosis Factor (Ligand) Superfamily, Member 11 蛋白 proteins categorized by available protein types. Additional protein types can be located using our search function.

Tumor Necrosis Factor (Ligand) Superfamily, Member 11 蛋白 by 应用范围

Find Tumor Necrosis Factor (Ligand) Superfamily, Member 11 蛋白 validated for a specific application such as WB, SDS, ELISA, Imm. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Tumor Necrosis Factor (Ligand) Superfamily, Member 11 蛋白 by 生物活性

Find Tumor Necrosis Factor (Ligand) Superfamily, Member 11 蛋白 with a specific 生物活性. The 生物活性 listed below are among those available. Click on a link to go to the corresponding products.

Popular Tumor Necrosis Factor (Ligand) Superfamily, Member 11 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7275517
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7275516
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7275518
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293T Cells
Validations
  • (2)
Cat. No. ABIN1323211
Quantity 25 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana benthamiana)
Validations
  • (2)
Cat. No. ABIN1019704
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source
Validations
  • (4)
  • (1)
Cat. No. ABIN1112027
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7013608
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN6253590
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN5674645
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN6386415
Quantity 200 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN6973285
Quantity 200 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7125527
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1323214
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1323212
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Human Cells
Validations
  • (1)
Cat. No. ABIN7320666
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our Tumor Necrosis Factor (Ligand) Superfamily, Member 11 蛋白

Nguyen, Nohe: "Factors that Affect the Osteoclastogenesis of RAW264.7 Cells." in: Journal of biochemistry and analytical studies, Vol. 2, Issue 1, (2017) (PubMed).

Beleut, Rajaram, Caikovski, Ayyanan, Germano, Choi, Schneider, Brisken: "Two distinct mechanisms underlie progesterone-induced proliferation in the mammary gland." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 7, pp. 2989-94, (2010) (PubMed).

DAmelio, Isaia, Isaia: "The osteoprotegerin/RANK/RANKL system: a bone key to vascular disease." in: Journal of endocrinological investigation, Vol. 32, Issue 4 Suppl, pp. 6-9, (2009) (PubMed).

Takahashi, Udagawa, Suda: "A new member of tumor necrosis factor ligand family, ODF/OPGL/TRANCE/RANKL, regulates osteoclast differentiation and function." in: Biochemical and biophysical research communications, Vol. 256, Issue 3, pp. 449-55, (1999) (PubMed).

Suda, Takahashi, Udagawa, Jimi, Gillespie, Martin: "Modulation of osteoclast differentiation and function by the new members of the tumor necrosis factor receptor and ligand families." in: Endocrine reviews, Vol. 20, Issue 3, pp. 345-57, (1999) (PubMed).

Yasuda, Shima, Nakagawa, Yamaguchi, Kinosaki, Mochizuki, Tomoyasu, Yano, Goto, Murakami, Tsuda, Morinaga, Higashio, Udagawa, Takahashi, Suda: "Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 95, Issue 7, pp. 3597-602, (1998) (PubMed).

Wong, Rho, Arron, Robinson, Orlinick, Chao, Kalachikov, Cayani, Bartlett, Frankel, Lee, Choi: "TRANCE is a novel ligand of the tumor necrosis factor receptor family that activates c-Jun N-terminal kinase in T cells." in: The Journal of biological chemistry, Vol. 272, Issue 40, pp. 25190-4, (1997) (PubMed).

Anderson, Maraskovsky, Billingsley, Dougall, Tometsko, Roux, Teepe, DuBose, Cosman, Galibert: "A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function." in: Nature, Vol. 390, Issue 6656, pp. 175-9, (1997) (PubMed).

Aliases for Tumor Necrosis Factor (Ligand) Superfamily, Member 11 蛋白

TNF superfamily member 11 (TNFSF11) 蛋白
tumor necrosis factor (ligand) superfamily, member 11 (Tnfsf11) 蛋白
TNF superfamily member 11 (Tnfsf11) 蛋白
TNF receptor superfamily member 11b (TNFRSF11B) 蛋白
TNF superfamily member 11 L homeolog (tnfsf11.L) 蛋白
CD254 蛋白
cd254 蛋白
hRANKL2 蛋白
Ly109l 蛋白
ODF 蛋白
odf 蛋白
OPG 蛋白
OPGL 蛋白
opgl 蛋白
OPTB2 蛋白
optb2 蛋白
RANKL 蛋白
rankl 蛋白
sOdf 蛋白
sodf 蛋白
TNFSF11 蛋白
tnfsf11 蛋白
TRANCE 蛋白
Trance 蛋白
trance 蛋白
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