TUBA1A 抗体
(Tubulin, alpha 1a (Tuba1a))
Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The genes encoding these microtubule constituents belong to the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species. This gene encodes alpha tubulin and is highly similar to the mouse and rat Tuba1 genes. Northern blotting studies have shown that the gene expression is predominantly found in morphologically differentiated neurologic cells. This gene is one of three alpha-tubulin genes in a cluster on chromosome 12q. Mutations in this gene cause lissencephaly type 3 (LIS3) - a neurological condition characterized by microcephaly, mental retardation, and early-onset epilepsy and caused by defective neuronal migration. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2012].
recommended
recommended
Tuba1a 适用: 人 ELISA, WB, IHC, IF, IP, FACS 宿主: 小鼠 Monoclonal 7E5C12 unconjugated
recommended
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TUBA1A 抗体 by 克隆形成能力
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Find TUBA1A 抗体 with a specific conjugate such as FITC, Biotin, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.
Popular TUBA1A 抗体
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Reactivity
Application
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Cat. No.
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Datasheet
Reactivity
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Application
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Validations
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Cat. No.
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Quantity
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Cat. No.
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Quantity
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Quantity
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Cat. No.
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Quantity
100 μg
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Datasheet
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Cat. No.
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Quantity
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Cat. No.
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Quantity
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Datasheet
Datasheet
Reactivity
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Application
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Validations
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Cat. No.
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Quantity
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Datasheet
Datasheet
Reactivity
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Application
ELISA
Validations
Cat. No.
ABIN7173652
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
ELISA, WB
Validations
Cat. No.
ABIN6389759
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
ELISA
Validations
Cat. No.
ABIN7173654
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Bat, Cow, Dog, Guinea Pig, Hamster, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat, Sheep, Xenopus laevis, Zebrafish (Danio rerio)
Application
WB
Validations
Cat. No.
ABIN6749217
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Bat, Chicken, Cow, Dog, Drosophila melanogaster, Guinea Pig, Hamster, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat, Xenopus laevis, Zebrafish (Danio rerio)
Application
WB
Validations
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Quantity
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Datasheet
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Latest Publications for our TUBA1A 抗体
: "Role of estrogen receptors and Src signaling in mechanisms of bone metastasis by estrogen receptor positive breast cancers." in: Journal of translational medicine, Vol. 15, Issue 1, pp. 97, (2018) (PubMed).: "Sequences in Linker-1 domain of the multidrug resistance associated protein (MRP1 or ABCC1) bind to tubulin and their binding is modulated by phosphorylation." in: Biochemical and biophysical research communications, Vol. 482, Issue 4, pp. 1001-1006, (2017) (PubMed).
: "Modulation of Wnt signaling is essential for the differentiation of ciliated epithelial cells in human airways." in: FEBS letters, Vol. 591, Issue 21, pp. 3493-3506, (2017) (PubMed).
: "Germline CBL mutations cause developmental abnormalities and predispose to juvenile myelomonocytic leukemia. ..." in: Nature genetics, Vol. 42, Issue 9, pp. 794-800, (2010) (PubMed).
: "Microtubule regulation in mitosis: tubulin phosphorylation by the cyclin-dependent kinase Cdk1." in: Molecular biology of the cell, Vol. 17, Issue 3, pp. 1041-50, (2006) (PubMed).
: "Post-translational modifications regulate microtubule function." in: Nature reviews. Molecular cell biology, Vol. 4, Issue 12, pp. 938-47, (2003) (PubMed).
Aliases for TUBA1A 抗体
tubulin, alpha 1A (Tuba1a) 抗体tubulin alpha 1a (TUBA1A) 抗体
tubulin, alpha 1a (TUBA1A) 抗体
tubulin alpha-1B chain (LOC608147) 抗体
tubulin alpha-1A chain (LOC100392817) 抗体
tubulin alpha-3 chain-like (LOC425049) 抗体
tubulin, alpha 1a (tuba1a) 抗体
alpha-Tubulin at 84B (alphaTub84B) 抗体
tubulin alpha-1A chain (LOC100051840) 抗体
tubulin alpha-1A chain (LOC100340483) 抗体
tubulin alpha-1A chain (LOC100726777) 抗体
tubulin alpha 1a L homeolog (tuba1a.L) 抗体
1t 抗体
a-tub84B 抗体
a1t 抗体
alpha-Tub 抗体
alpha-tub 抗体
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alpha-tubulin 抗体
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