Tryptophan Hydroxylase 2 产品
(Tryptophan Hydroxylase 2 (TPH2))
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This gene encodes a member of the pterin-dependent aromatic acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. The human genome contains two related tryptophan hydroxylases, one on chromosome 11p15-p14 and one on chromosome 12q21. This gene is expressed predominantly in the brain stem. Mutations in this gene may be associated with psychiatric diseases such as bipolar affective disorder and major depression. [provided by RefSeq, Jul 2008].
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Featured Tryptophan Hydroxylase 2 Categories
Tryptophan Hydroxylase 2 抗体
High quality antibodies with extensive validation data.
Tryptophan Hydroxylase 2 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
Tryptophan Hydroxylase 2 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Tryptophan Hydroxylase 2 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, IHC, FACS, IF
Validations
- (5)
Cat. No.
ABIN185533
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (4)
Cat. No.
ABIN7173617
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
IHC
Validations
- (4)
Cat. No.
ABIN7456102
Quantity
100 μg
Datasheet
Datasheet
Recommended Tryptophan Hydroxylase 2 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6975576
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6960228
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6960229
Quantity
96 tests
Datasheet
Datasheet
Recommended Tryptophan Hydroxylase 2 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7125512
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Rat
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7408504
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7398893
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our Tryptophan Hydroxylase 2 Products
: "Identification of Embryonic Neural Plate Border Stem Cells and Their Generation by Direct Reprogramming from Adult Human Blood Cells." in: Cell stem cell, Vol. 24, Issue 1, pp. 166-182.e13, (2019) (PubMed).: "Acute perturbation of Pet1-neuron activity in neonatal mice impairs cardiorespiratory homeostatic recovery." in: eLife, Vol. 7, (2019) (PubMed).
: "Cav1.2 L-type calcium channels regulate stress coping behavior via serotonin neurons." in: Neuropharmacology, Vol. 144, pp. 282-290, (2019) (PubMed).
: "Rostral and Caudal Ventral Tegmental Area GABAergic Inputs to Different Dorsal Raphe Neurons Participate in Opioid Dependence." in: Neuron, Vol. 101, Issue 4, pp. 748-761.e5, (2019) (PubMed).
: "Single-cell transcriptomes and whole-brain projections of serotonin neurons in the mouse dorsal and median raphe nuclei." in: eLife, Vol. 8, (2019) (PubMed).
: "Xiaochaihutang attenuates depressive/anxiety-like behaviors of social isolation-reared mice by regulating monoaminergic system, neurogenesis and BDNF expression." in: Journal of ethnopharmacology, Vol. 208, pp. 94-104, (2018) (PubMed).
: "Anatomically Defined and Functionally Distinct Dorsal Raphe Serotonin Sub-systems." in: Cell, Vol. 175, Issue 2, pp. 472-487.e20, (2018) (PubMed).
: "SSRIs target prefrontal to raphe circuits during development modulating synaptic connectivity and emotional behavior." in: Molecular psychiatry, (2018) (PubMed).
: "Gene Expression Profiling with Cre-Conditional Pseudorabies Virus Reveals a Subset of Midbrain Neurons That Participate in Reward Circuitry." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 37, Issue 15, pp. 4128-4144, (2017) (PubMed).
: "Prenatal and lactational bisphenol A exposure does not alter serotonergic neurons morphologically in the murine dorsal raphe nucleus." in: Brain & development, Vol. 39, Issue 6, pp. 475-482, (2017) (PubMed).
Synonyms and alternative names related to Tryptophan Hydroxylase 2
tryptophan hydroxylase 2 (TPH2), tryptophan hydroxylase 2 (Tph2), tryptophan hydroxylase 2 (tph2), tryptophan hydroxylase 2 (tryptophan 5-monooxygenase) (tph2), ADHD7, AU043594, NTPH, Ntph, tphR, wu:fq15a04Protein level used designations for Tryptophan Hydroxylase 2
- neuronal tryptophan hydroxylase
- tryptophan 5-hydroxylase 2
- tryptophan 5-monooxygenase 2
- tryptophan hydroxylase-2
- tryptophan hydroxylase 2
- tryptophan 5-hydroxylase 2-like
- tph2a
- tryptophan hydroxylase R
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