TRRAP 产品
(Transformation/transcription Domain-Associated Protein (TRRAP))
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This gene encodes a large multidomain protein of the phosphoinositide 3-kinase-related kinases (PIKK) family. The encoded protein is a common component of many histone acetyltransferase (HAT) complexes and plays a role in transcription and DNA repair by recruiting HAT complexes to chromatin. Deregulation of this gene may play a role in several types of cancer including glioblastoma multiforme. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011].
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Featured TRRAP Categories
TRRAP 抗体
High quality antibodies with extensive validation data.
TRRAP ELISA试剂盒
Reliable ELISA kits for a wide range of species.
Recommended TRRAP 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (3)
Cat. No.
ABIN6243321
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Mouse
Application
WB
Validations
- (1)
Cat. No.
ABIN6243320
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, ICC
Validations
- (2)
Cat. No.
ABIN5014439
Quantity
100 μL
Datasheet
Datasheet
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Latest Publications for our TRRAP Products
: "ATAC and Mediator coactivators form a stable complex and regulate a set of non-coding RNA genes." in: EMBO reports, Vol. 11, Issue 7, pp. 541-7, (2010) (PubMed).: "Formation of an active tissue-specific chromatin domain initiated by epigenetic marking at the embryonic stem cell stage." in: Molecular and cellular biology, Vol. 25, Issue 5, pp. 1804-20, (2005) (PubMed).
: "c-Myc transformation domain recruits the human STAGA complex and requires TRRAP and GCN5 acetylase activity for transcription activation." in: The Journal of biological chemistry, Vol. 278, Issue 22, pp. 20405-12, (2003) (PubMed).
: "The adenovirus E1A oncoprotein recruits the cellular TRRAP/GCN5 histone acetyltransferase complex." in: Oncogene, Vol. 22, Issue 18, pp. 2836-41, (2003) (PubMed).
: "The DNA sequence of human chromosome 7. ..." in: Nature, Vol. 424, Issue 6945, pp. 157-64, (2003) (PubMed).
Synonyms and alternative names related to TRRAP
transformation/transcription domain associated protein (TRRAP), phosphotransferases/inositol or phosphatidylinositol kinase (AT4G36080), transcription-associated protein 1 (LOC5577036), transformation/transcription domain-associated protein (Trrap), transformation/transcription domain-associated protein (trrap), transformation/transcription domain associated protein (trrap), transformation/transcription domain-associated protein (TRRAP), transformation/transcription domain-associated protein (LOC100637779), AI481500, PAF350/400, PAF400, STAF40, TR-AP, Tra1, TRRAP, trrapProtein level used designations for TRRAP
- 350/400 kDa PCAF-associated factor
- tra1 homolog
- transformation/transcription domain-associated protein
- transactivation/transformation-domain associated protein
- transformation/transcription domain-associated protein-like
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