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TRPM6 产品

(Transient Receptor Potential Cation Channel, Subfamily M, Member 6 (TRPM6))
This gene is predominantly expressed in the kidney and colon, and encodes a protein containing an ion channel domain and a protein kinase domain. It is crucial for magnesium homeostasis, and plays an essential role in epithelial magnesium transport and in the active magnesium absorption in the gut and kidney. Mutations in this gene are associated with hypomagnesemia with secondary hypocalcemia. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Apr 2010].

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Featured TRPM6 Categories

TRPM6 抗体

High quality antibodies with extensive validation data.

TRPM6 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

TRPM6 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended TRPM6 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application IHC, ELISA, IF
Validations
  • (2)
Cat. No. ABIN7172868
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (3)
  • (2)
Cat. No. ABIN392616
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application IHC, ELISA, WB
Validations
  • (3)
Cat. No. ABIN3029237
Quantity 0.4 mL
Datasheet Datasheet

Recommended TRPM6 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6960126
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN5674671
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN5674672
Quantity 96 tests
Datasheet Datasheet

Recommended TRPM6 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7398629
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN6383237
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our TRPM6 Products

Furukawa, Fujii, Manabe, Matsunaga, Endo, Hasegawa, Ito, Yamaguchi, Yamazaki, Ikari: "Up-Regulation of Transient Receptor Potential Melastatin 6 Channel Expression by Tumor Necrosis Factor-α in the Presence of Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor." in: Journal of cellular physiology, Vol. 232, Issue 10, pp. 2841-2850, (2017) (PubMed).

Lee, Chen, Ng, Lai, Lien: "Renal adaptation to gentamicin-induced mineral loss." in: American journal of nephrology, Vol. 35, Issue 3, pp. 279-86, (2012) (PubMed).

Ikari, Okude, Sawada, Takahashi, Sugatani, Miwa: "Down-regulation of TRPM6-mediated magnesium influx by cyclosporin A." in: Naunyn-Schmiedeberg's archives of pharmacology, Vol. 377, Issue 4-6, pp. 333-43, (2008) (PubMed).

Ikari, Okude, Sawada, Yamazaki, Sugatani, Miwa: "TRPM6 expression and cell proliferation are up-regulated by phosphorylation of ERK1/2 in renal epithelial cells." in: Biochemical and biophysical research communications, Vol. 369, Issue 4, pp. 1129-33, (2008) (PubMed).

Cantrell: "Phosphoinositide 3-kinase signalling pathways." in: Journal of cell science, Vol. 114, Issue Pt 8, pp. 1439-45, (2001) (PubMed).

Blume-Jensen, Hunter: "Oncogenic kinase signalling." in: Nature, Vol. 411, Issue 6835, pp. 355-65, (2001) (PubMed).

Jhiang: "The RET proto-oncogene in human cancers." in: Oncogene, Vol. 19, Issue 49, pp. 5590-7, (2000) (PubMed).

Synonyms and alternative names related to TRPM6

transient receptor potential cation channel subfamily M member 6 (TRPM6), transient receptor potential cation channel, subfamily M, member 6 (Trpm6), CHAK2, HMGX, HOMG, HOMG1, HSH, TRPM6, TRPM6/CHAK2

Protein level used designations for TRPM6

  • transient receptor potential cation channel, subfamily M, member 6
  • channel kinase 2
  • melastatin-related TRP cation channel 6
  • transient receptor potential cation channel subfamily M member 6
  • transient receptor potential cation channel 6/channel-kinase 2
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