TRPM2 产品
(Transient Receptor Potential Cation Channel, Subfamily M, Member 2 (TRPM2))
Categories
The protein encoded by this gene is a calcium-permeable cation channel that is regulated by free intracellular ADP-ribose. The encoded protein is activated by oxidative stress and confers susceptibility to cell death. Several alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Jul 2008].
antibodies-online.com stands for high-quality research products. Search, find and order tools with extensive validation data, images, references. Our scientific customer service is always at your disposal if you have any questions about the selection or application of our products.
Featured TRPM2 Categories
TRPM2 抗体
High quality antibodies with extensive validation data.
Recommended TRPM2 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
IHC, WB, ELISA, IF
Validations
- (6)
Cat. No.
ABIN7172859
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
IHC, WB, ELISA
Validations
- (3)
Cat. No.
ABIN7172857
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Guinea Pig, Human, Mouse, Rat
Application
IHC, WB, IHC (p)
Validations
- (3)
Cat. No.
ABIN490062
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our TRPM2 Products
: "Novel CaM-binding motif in its NudT9H domain contributes to temperature sensitivity of TRPM2." in: Biochimica et biophysica acta. Molecular cell research, (2018) (PubMed).: "Paradoxical lower sensitivity of Locus Coeruleus than Substantia Nigra pars compacta neurons to acute actions of rotenone." in: Experimental neurology, Vol. 287, Issue Pt 1, pp. 34-43, (2016) (PubMed).
: "The role of TRPM2 in hydrogen peroxide-induced expression of inflammatory cytokine and chemokine in rat trigeminal ganglia." in: Neuroscience, Vol. 297, pp. 160-9, (2015) (PubMed).
: "ADP-ribose/TRPM2-mediated Ca2+ signaling is essential for cytolytic degranulation and antitumor activity of natural killer cells." in: Scientific reports, Vol. 5, pp. 9482, (2015) (PubMed).
: "The enzymatic activities of CD38 enhance CLL growth and trafficking: implications for therapeutic targeting." in: Leukemia, Vol. 29, Issue 2, pp. 356-68, (2015) (PubMed).
: "TNF-α-mediated caspase-8 activation induces ROS production and TRPM2 activation in adult ventricular myocytes." in: Cardiovascular research, Vol. 103, Issue 1, pp. 90-9, (2014) (PubMed).
: "Oxidative stress increases pulmonary vascular permeability in diabetic rats through activation of transient receptor potential melastatin 2 channels." in: Microcirculation (New York, N.Y. : 1994), Vol. 21, Issue 8, pp. 754-60, (2014) (PubMed).
: "Structure-activity relationship of adenosine 5'-diphosphoribose at the transient receptor potential melastatin 2 (TRPM2) channel: rational design of antagonists." in: Journal of medicinal chemistry, Vol. 56, Issue 24, pp. 10079-102, (2013) (PubMed).
: "TRPM2 cation channels modulate T cell effector functions and contribute to autoimmune CNS inflammation." in: PLoS ONE, Vol. 7, Issue 10, pp. e47617, (2012) (PubMed).
: "Expression and functional properties of TRPM2 channels in dopaminergic neurons of the substantia nigra of the rat." in: Journal of neurophysiology, Vol. 106, Issue 6, pp. 2865-75, (2011) (PubMed).
Synonyms and alternative names related to TRPM2
transient receptor potential cation channel subfamily M member 2 (TRPM2), transient receptor potential cation channel, subfamily M, member 2 (Trpm2), transient receptor potential cation channel, subfamily M, member 2 (trpm2), transient receptor potential cation channel subfamily C member 7 (TRPC7), transient receptor potential cation channel subfamily M member 2 (trpm2), transient receptor potential cation channel subfamily M member 2 (Trpm2), 9830168K16Rik, C79133, EREG1, KNP3, LTRPC2, NUDT9H, NUDT9L1, si:ch73-263b18.1, Trp7, TRPC7, TRPM2, Trpm2-predicted, Trrp7Protein level used designations for TRPM2
- LTrpC-2
- estrogen-responsive element-associated gene 1 protein
- long transient receptor potential channel 2
- transient receptor potential cation channel subfamily M member 2
- transient receptor potential channel 7
- transient receptor potential melastatin family 2
- transient receptor potential cation channel, subfamily M, member 2
- transient receptor potential cation channel, subfamily C, member 7
- transient receptor potential cation channel, subfamily C, member 7-like
- transient receptor potential cation channel subfamily M member 2-like
- transient receptor protein 7
You are here:
