TRPC5 产品
(Transient Receptor Potential Cation Channel, Subfamily C, Member 5 (TRPC5))
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This gene belongs to the transient receptor family. It encodes one of the seven mammalian TRPC (transient receptor potential channel) proteins. The encoded protein is a multi-pass membrane protein and is thought to form a receptor-activated non-selective calcium permeant cation channel. The protein is active alone or as a heteromultimeric assembly with TRPC1, TRPC3, and TRPC4. It also interacts with multiple proteins including calmodulin, CABP1, enkurin, Na(+)-H+ exchange regulatory factor (NHERF ), interferon-induced GTP-binding protein (MX1), ring finger protein 24 (RNF24), and SEC14 domain and spectrin repeat-containing protein 1 (SESTD1). [provided by RefSeq, May 2010].
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Featured TRPC5 Categories
Recommended TRPC5 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, AA
Validations
- (4)
- (1)
Cat. No.
ABIN2485379
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, AA
Validations
- (4)
Cat. No.
ABIN863137
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, AA
Validations
- (4)
Cat. No.
ABIN2485380
Quantity
100 μg
Datasheet
Datasheet
Recommended TRPC5 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6208032
Quantity
96 tests
Datasheet
Datasheet
Recommended TRPC5 蛋白
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Reactivity
Source
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Quantity
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Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1323824
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3119054
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3137367
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our TRPC5 Products
: "Functional interplay between ganglioside GM1 and cross-linking galectin-1 induces axon-like neuritogenesis via integrin-based signaling and TRPC5-dependent Ca²⁺ influx." in: Journal of neurochemistry, Vol. 136, Issue 3, pp. 550-63, (2016) (PubMed).: "Increased TRPC5 glutathionylation contributes to striatal neuron loss in Huntington's disease." in: Brain : a journal of neurology, (2015) (PubMed).
: "Decreased anxiety-like behavior and Gαq/11-dependent responses in the amygdala of mice lacking TRPC4 channels." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 34, Issue 10, pp. 3653-67, (2014) (PubMed).
: "Insulin excites anorexigenic proopiomelanocortin neurons via activation of canonical transient receptor potential channels." in: Cell metabolism, Vol. 19, Issue 4, pp. 682-93, (2014) (PubMed).
: "Canonical transient receptor channel 5 (TRPC5) and TRPC1/4 contribute to seizure and excitotoxicity by distinct cellular mechanisms." in: Molecular pharmacology, Vol. 83, Issue 2, pp. 429-38, (2013) (PubMed).
: "Leptin promotes K(ATP) channel trafficking by AMPK signaling in pancreatic ?-cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 31, pp. 12673-8, (2013) (PubMed).
: "Insulin increases surface expression of TRPC6 channels in podocytes: role of NADPH oxidases and reactive oxygen species." in: American journal of physiology. Renal physiology, Vol. 302, Issue 3, pp. F298-307, (2012) (PubMed).
: "Selective G?i subunits as novel direct activators of transient receptor potential canonical (TRPC)4 and TRPC5 channels." in: The Journal of biological chemistry, Vol. 287, Issue 21, pp. 17029-39, (2012) (PubMed).
: "Calpain cleaves and activates the TRPC5 channel to participate in semaphorin 3A-induced neuronal growth cone collapse." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 20, pp. 7888-92, (2012) (PubMed).
: "Mechanisms and roles of muscarinic activation in guinea-pig adrenal medullary cells." in: American journal of physiology. Cell physiology, Vol. 303, Issue 6, pp. C635-44, (2012) (PubMed).
Synonyms and alternative names related to TRPC5
transient receptor potential cation channel, subfamily C, member 5a (trpc5a), transient receptor potential cation channel subfamily C member 5 (TRPC5), transient receptor potential cation channel, subfamily C, member 5 (Trpc5), CCE2, trp, TRP-5, TRP5, trpc5, TRPC5, Trpc5, Trrp5, wu:fi73f08Protein level used designations for TRPC5
- transient receptor potential cation channel, subfamily C, member 5
- transient receptor potential channel subfamily C member 5
- CCE2
- rtrp5
- short transient receptor potential channel 5
- TRP-5
- hTRP5
- transient receptor potential channel 5
- transient receptor protein 5
- capacitative calcium entry channel 2
- mtrp5
- trp-related protein 5
- vtransient receptor potential cation channel, subfamily C, member 5
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