TRP63 产品
(Transformation Related Protein 63 (TRP63))
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This gene encodes tumor protein p63, a member of the p53 family of transcription factors involved in cellular responses to stress and development. The family members include tumor proteins p53, p63, and p73, which have high sequence similarity to one another. This similarity allows p63 and p73 to transactivate p53-responsive genes causing cell cycle arrest and apoptosis. The family members can interact with each other in many ways, including direct and indirect protein interactions. This results in mutual regulation of target gene promoters. Tumor protein p63 -/- mice have several developmental defects which include the lack of limbs and other tissues, such as teeth and mammary glands, which develop as a result of interactions between mesenchyme and epithelium. Both alternative splicing and the use of alternative promoters result in multiple transcript variants encoding different protein isoforms.[provided by RefSeq, Dec 2009].
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TRP63 抗体
High quality antibodies with extensive validation data.
Recommended TRP63 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
Cat. No.
ABIN1019670
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application
WB
Validations
- (1)
Cat. No.
ABIN2778222
Quantity
100 μL
Datasheet
Datasheet
Synonyms and alternative names related to TRP63
transformation related protein 63 (Trp63), AI462811, Ket, P51/P63, P63, P73l, Tp63, Trp53rp1Protein level used designations for TRP63
- transformation-related protein 63
- tumor protein 63
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