Tropomyosin 1 (Alpha) 抗体
(Tropomyosin 1 (Alpha) (TPM1))
This gene is a member of the tropomyosin family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosin is composed of two alpha-helical chains arranged as a coiled-coil. It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments. The encoded protein is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle, where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction. In smooth muscle and non-muscle cells, alternatively spliced transcript variants encoding a range of isoforms have been described. Mutations in this gene are associated with type 3 familial hypertrophic cardiomyopathy. [provided by RefSeq, Jul 2008].
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Find Tropomyosin 1 (Alpha) 抗体 with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.
Popular Tropomyosin 1 (Alpha) 抗体
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Quantity
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Quantity
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Quantity
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Datasheet
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Quantity
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Datasheet
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Quantity
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Datasheet
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Reactivity
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Application
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Quantity
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Datasheet
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Reactivity
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Application
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Validations
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Quantity
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Datasheet
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Latest Publications for our Tropomyosin 1 (Alpha) 抗体
: "Disruption of cardiac thin filament assembly arising from a mutation in LMOD2: A novel mechanism of neonatal dilated cardiomyopathy." in: Science advances, Vol. 5, Issue 9, pp. eaax2066, (2019) (PubMed).: "Quantitative Proteomics Analysis Reveals Novel Targets of miR-21 in Zebrafish Embryos." in: Scientific reports, Vol. 7, Issue 1, pp. 4022, (2018) (PubMed).
: "From the Cover: Neutralization of terminal differentiation in gliomagenesis." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 36, pp. 14520-7, (2013) (PubMed).
: "Osteopontin regulates α-smooth muscle actin and calponin in vascular smooth muscle cells." in: Cell biology international, Vol. 36, Issue 2, pp. 155-61, (2012) (PubMed).
: "Role of the head-to-tail overlap region in smooth and skeletal muscle beta-tropomyosin." in: Biochemistry, Vol. 47, Issue 1, pp. 388-97, (2008) (PubMed).
: "Tropomyosin-based regulation of the actin cytoskeleton in time and space." in: Physiological reviews, Vol. 88, Issue 1, pp. 1-35, (2008) (PubMed).
: "Tropomyosin's periods are quasi-equivalent for actin binding but have specific regulatory functions." in: Biochemistry, Vol. 46, Issue 51, pp. 14917-27, (2007) (PubMed).
: "From gene expression analysis to tissue microarrays: a rational approach to identify therapeutic and diagnostic targets in lymphoid malignancies." in: Molecular & cellular proteomics : MCP, Vol. 5, Issue 6, pp. 1072-81, (2006) (PubMed).
Aliases for Tropomyosin 1 (Alpha) 抗体
tropomyosin 1 (alpha) (TPM1) 抗体tropomyosin (tm7) 抗体
tropomyosin 1 (TPM1) 抗体
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tropomyosin 1 (Tpm1) 抗体
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