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TRIM72 产品

(Tripartite Motif Containing 72 (TRIM72))

Categories

Muscle-specific protein that plays a central role in cell membrane repair by nucleating the assembly of the repair machinery at injury sites. Specifically binds phosphatidylserine. extracellular oxidative environment results in disulfide bond formation and homooligomerization at the injury site. This oligomerization acts as a nucleation site for recruitment of TRIM72-containing vesicles to the injury site, leading to membrane patch formation. Probably acts upstream of the Ca(2+)-dependent membrane resealing process. Required for transport of DYSF to sites of cell injury during repair patch formation. Regulates membrane budding and exocytosis. May be involved in the regulation of the mobility of KCNB1-containing endocytic vesicles (By similarity).

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Featured TRIM72 Categories

TRIM72 抗体

High quality antibodies with extensive validation data.

TRIM72 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

TRIM72 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended TRIM72 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IP
Validations
  • (1)
  • (3)
Cat. No. ABIN531817
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC
Validations
  • (2)
Cat. No. ABIN3181504
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IP
Validations
  • (2)
Cat. No. ABIN949979
Quantity 100 μL
Datasheet Datasheet

Recommended TRIM72 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6970868
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6975088
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6974917
Quantity 96 tests
Datasheet Datasheet

Recommended TRIM72 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1323751
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1323753
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3096029
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our TRIM72 Products

Lemckert, Bournazos, Eckert, Kenzler, Hawkes, Butler, Ceely, North, Winlaw, Egan, Cooper: "Lack of MG53 in human heart precludes utility as a biomarker of myocardial injury or endogenous cardioprotective factor." in: Cardiovascular research, Vol. 110, Issue 2, pp. 178-87, (2016) (PubMed).

Cheng, Zhang, Gao, Ali Samie, Azar, Tsang, Dong, Sahoo, Li, Zhuo, Garrity, Wang, Ferrer, Dowling, Xu, Han, Xu: "The intracellular Ca²⁺ channel MCOLN1 is required for sarcolemma repair to prevent muscular dystrophy." in: Nature medicine, Vol. 20, Issue 10, pp. 1187-92, (2014) (PubMed).

Park, Kwon, Jeong, Yi, Lee, Ko, Song: "Crystal structure of PRY-SPRY domain of human TRIM72." in: Proteins, Vol. 78, Issue 3, pp. 790-5, (2010) (PubMed).

Martin, Han, Gordon, Terry, Prabhakar, She, Xie, Hellsten, Chan, Altherr, Couronne, Aerts, Bajorek, Black, Blumer, Branscomb, Brown, Bruno, Buckingham, Callen, Campbell, Campbell, Campbell, Caoile et al.: "The sequence and analysis of duplication-rich human chromosome 16. ..." in: Nature, Vol. 432, Issue 7020, pp. 988-94, (2004) (PubMed).

Synonyms and alternative names related to TRIM72

tripartite motif containing 72 (TRIM72), tripartite motif containing 72, E3 ubiquitin protein ligase L homeolog (trim72.L), tripartite motif-containing 72 (Trim72), tripartite motif containing 72 (Trim72), BC067209, MG53, Mg53, RGD1562778, Trim72

Protein level used designations for TRIM72

  • tripartite motif-containing 72
  • mitsugumin-53
  • tripartite motif-containing protein 72
  • Mitsugumin-53
  • mitsugumin 53
  • mg53
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