TRIM72 产品
(Tripartite Motif Containing 72 (TRIM72))
Categories
Muscle-specific protein that plays a central role in cell membrane repair by nucleating the assembly of the repair machinery at injury sites. Specifically binds phosphatidylserine. extracellular oxidative environment results in disulfide bond formation and homooligomerization at the injury site. This oligomerization acts as a nucleation site for recruitment of TRIM72-containing vesicles to the injury site, leading to membrane patch formation. Probably acts upstream of the Ca(2+)-dependent membrane resealing process. Required for transport of DYSF to sites of cell injury during repair patch formation. Regulates membrane budding and exocytosis. May be involved in the regulation of the mobility of KCNB1-containing endocytic vesicles (By similarity).
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Featured TRIM72 Categories
TRIM72 抗体
High quality antibodies with extensive validation data.
TRIM72 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
TRIM72 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended TRIM72 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IP
Validations
- (1)
- (3)
Cat. No.
ABIN531817
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC
Validations
- (2)
Cat. No.
ABIN3181504
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IP
Validations
- (2)
Cat. No.
ABIN949979
Quantity
100 μL
Datasheet
Datasheet
Recommended TRIM72 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6970868
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6975088
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6974917
Quantity
96 tests
Datasheet
Datasheet
Recommended TRIM72 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1323751
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1323753
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3096029
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our TRIM72 Products
: "Lack of MG53 in human heart precludes utility as a biomarker of myocardial injury or endogenous cardioprotective factor." in: Cardiovascular research, Vol. 110, Issue 2, pp. 178-87, (2016) (PubMed).: "The intracellular Ca²⁺ channel MCOLN1 is required for sarcolemma repair to prevent muscular dystrophy." in: Nature medicine, Vol. 20, Issue 10, pp. 1187-92, (2014) (PubMed).
: "Crystal structure of PRY-SPRY domain of human TRIM72." in: Proteins, Vol. 78, Issue 3, pp. 790-5, (2010) (PubMed).
: "The sequence and analysis of duplication-rich human chromosome 16. ..." in: Nature, Vol. 432, Issue 7020, pp. 988-94, (2004) (PubMed).
Synonyms and alternative names related to TRIM72
tripartite motif containing 72 (TRIM72), tripartite motif containing 72, E3 ubiquitin protein ligase L homeolog (trim72.L), tripartite motif-containing 72 (Trim72), tripartite motif containing 72 (Trim72), BC067209, MG53, Mg53, RGD1562778, Trim72Protein level used designations for TRIM72
- tripartite motif-containing 72
- mitsugumin-53
- tripartite motif-containing protein 72
- Mitsugumin-53
- mitsugumin 53
- mg53
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