TREX1 产品
(three Prime Repair Exonuclease 1 (TREX1))
Categories
This gene encodes a nuclear protein with 3' exonuclease activity. The encoded protein may play a role in DNA repair and serve as a proofreading function for DNA polymerase. Mutations in this gene result in Aicardi-Goutieres syndrome, chilblain lupus, Cree encephalitis, and other diseases of the immune system. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2012].
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Featured TREX1 Categories
Recommended TREX1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB
Validations
- (2)
- (8)
Cat. No.
ABIN524703
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IP
Validations
- (3)
Cat. No.
ABIN7172071
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (3)
Cat. No.
ABIN6149486
Quantity
100 μL
Datasheet
Datasheet
Recommended TREX1 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6970621
Quantity
96 tests
Datasheet
Datasheet
Recommended TREX1 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1323580
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1323578
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7419013
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our TREX1 Products
: "Downregulation of cytoplasmic DNases is implicated in cytoplasmic DNA accumulation and SASP in senescent cells." in: Nature communications, Vol. 9, Issue 1, pp. 1249, (2018) (PubMed).: "DNase-active TREX1 frame-shift mutants induce serologic autoimmunity in mice." in: Journal of autoimmunity, Vol. 81, pp. 13-23, (2017) (PubMed).
: "Human three prime exonuclease TREX1 is induced by genotoxic stress and involved in protection of glioma and melanoma cells to anticancer drugs." in: Biochimica et biophysica acta, Vol. 1833, Issue 8, pp. 1832-43, (2013) (PubMed).
: "Three prime exonuclease I (TREX1) is Fos/AP-1 regulated by genotoxic stress and protects against ultraviolet light and benzo(a)pyrene-induced DNA damage." in: Nucleic acids research, Vol. 38, Issue 19, pp. 6418-32, (2010) (PubMed).
: "A human DNA editing enzyme homologous to the Escherichia coli DnaQ/MutD protein." in: The EMBO journal, Vol. 18, Issue 13, pp. 3868-75, (1999) (PubMed).
: "Identification and expression of the TREX1 and TREX2 cDNA sequences encoding mammalian 3'-->5' exonucleases." in: The Journal of biological chemistry, Vol. 274, Issue 28, pp. 19655-60, (1999) (PubMed).
Synonyms and alternative names related to TREX1
three prime repair exonuclease 1 (CpipJ_CPIJ012074), three prime repair exonuclease 1 (Tsp_03749), three prime repair exonuclease 1 (TREX1), three prime repair exonuclease 1 (Trex1), 1661, AGS1, AU041952, CRV, DRN3, HERNS, RGD1309596Protein level used designations for TREX1
- three prime repair exonuclease 1
- 3' repair exonuclease 1
- 3'-5' exonuclease TREX1
- DNase III
- deoxyribonuclease III
- three prime exonuclease 1
- trophoblast expressed 1
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