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Transforming Growth Factor, beta 2 产品

(Transforming Growth Factor, beta 2 (TGFB2))

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This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types by transducing their signal through combinations of transmembrane type I and type II receptors (TGFBR1 and TGFBR2) and their downstream effectors, the SMAD proteins. Disruption of the TGFB/SMAD pathway has been implicated in a variety of human cancers. The encoded protein is secreted and has suppressive effects of interleukin-2 dependent T-cell growth. Translocation t(1\;7)(q41\;p21) between this gene and HDAC9 is associated with Peters' anomaly, a congenital defect of the anterior chamber of the eye. The knockout mice lacking this gene show perinatal mortality and a wide range of developmental, including cardiac, defects. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Sep 2010].

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Featured Transforming Growth Factor, beta 2 Categories

Transforming Growth Factor, beta 2 抗体

High quality antibodies with extensive validation data.

Transforming Growth Factor, beta 2 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

Transforming Growth Factor, beta 2 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Transforming Growth Factor, beta 2 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, ELISA, IF
Validations
  • (6)
Cat. No. ABIN3029221
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (4)
Cat. No. ABIN7429457
Quantity 100 μL
Datasheet Datasheet
Reactivity Rat
Application WB, IHC, IP, ICC
Validations
  • (4)
Cat. No. ABIN7429460
Quantity 100 μL
Datasheet Datasheet

Recommended Transforming Growth Factor, beta 2 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6960089
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6960093
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6960096
Quantity 96 tests
Datasheet Datasheet

Recommended Transforming Growth Factor, beta 2 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Tobacco (Nicotiana benthamiana)
Validations
  • (4)
  • (2)
Cat. No. ABIN1112028
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7275710
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7275711
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our Transforming Growth Factor, beta 2 Products

Liu, Bell, Herrmann, Arnhold, Mercieca, Anders, Nagel-Wolfrum, Thanos, Prokosch: "Crystallins Play a Crucial Role in Glaucoma and Promote Neuronal Cell Survival in an In Vitro Model Through Modulating Müller Cell Secretion." in: Investigative ophthalmology & visual science, Vol. 63, Issue 8, pp. 3, (2022) (PubMed).

Singh, Veeriah, Xi, Labella, Chen, Romeo, Ramasamy, Kusumbe: "Angiocrine signals regulate quiescence and therapy resistance in bone metastasis." in: JCI insight, Vol. 4, Issue 13, (2020) (PubMed).

Xing, Xiao, Lu, Zhu, He, Huang, Lopez, Wong, Ju, Tian, Zhang, Xu, Wang, Li, Karin, Ren: "GFI1 downregulation promotes inflammation-linked metastasis of colorectal cancer." in: Cell death and differentiation, Vol. 24, Issue 5, pp. 929-943, (2018) (PubMed).

Song, Zhang, Zhang, Du, Guo, Kuang, Wang, Wu, Zou, Zou, Lv, Wang: "A microfluidic device for studying chemotaxis mechanism of bacterial cancer targeting." in: Scientific reports, Vol. 8, Issue 1, pp. 6394, (2018) (PubMed).

Gupta, Donahue, Sandoval-Cooper, Castellino, Ploplis: "Plasminogen Activator Inhibitor-1 Protects Mice Against Cardiac Fibrosis by Inhibiting Urokinase-type Plasminogen Activator-mediated Plasminogen Activation." in: Scientific reports, Vol. 7, Issue 1, pp. 365, (2017) (PubMed).

Noh, Abdul Kadir, Crowston, Subrayan, Vasudevan: "Effects of ranibizumab on TGF-β1 and TGF-β2 production by human Tenon's fibroblasts: An in vitro study." in: Molecular vision, Vol. 21, pp. 1191-200, (2016) (PubMed).

Wu, Fang, Shen, Liu: "SP600125 promotes resolution of allergic airway inflammation via TLR9 in an OVA-induced murine acute asthma model." in: Molecular immunology, (2015) (PubMed).

Li, Li, Sun, Peng, Zhao, Zhong et al.: "Influence of the Expression Level of O6-Alkylguanine-DNA Alkyltransferase on the Formation of DNA Interstrand Crosslinks Induced by Chloroethylnitrosoureas in Cells: A Quantitation Using ..." in: PLoS ONE, Vol. 10, Issue 3, pp. e0121225, (2015) (PubMed).

Li, Liu, Shen, Wang, Chen, Xu, Wen: "MicroRNA-26a modulates transforming growth factor beta-1-induced proliferation in human fetal lung fibroblasts." in: Biochemical and biophysical research communications, Vol. 454, Issue 4, pp. 512-517, (2014) (PubMed).

Li, Wang, Zhang, Zhao, Huang, Wu, Li, Li, Liu, Cao, Dai, Fang, Shang, Cao, Zhao, Chen: "Elevated PLGF contributes to small-cell lung cancer brain metastasis." in: Oncogene, Vol. 32, Issue 24, pp. 2952-62, (2013) (PubMed).

Synonyms and alternative names related to Transforming Growth Factor, beta 2

transforming growth factor beta 2 (TGFB2), transforming growth factor beta 2 L homeolog (tgfb2.L), transforming growth factor, beta 2 (Tgfb2), transforming growth factor, beta receptor 2 (Tgfbr2), transforming growth factor, beta 2 (tgfb2), transforming growth factor beta 2 (Tgfb2), BB105277, LDS4, MGF, TGF-B2, TGF-beta2, tgf-beta2, Tgf-beta2, TGF-beta 2, Tgfb-2, TGFB2, tgfb2-A, TGFbeta2, Tgfbr2T

Protein level used designations for Transforming Growth Factor, beta 2

  • BSC-1 cell growth inhibitor
  • G-TSF
  • cetermin
  • glioblastoma-derived T-cell suppressor factor
  • polyergin
  • transforming growth factor beta-2
  • TGF-beta 2
  • TGF-beta-2
  • prepro-polypeptide
  • Transforming growth factor beta-2
  • transforming growth factor beta 2
  • TGF-beta receptor type II
  • TGF-beta receptor type-2
  • TGF-beta type II receptor
  • TGFR-2
  • tbetaR-II
  • transforming growth factor beta receptor type II
  • transforming growth factor beta, receptor 2
  • transforming growth factor, beta receptor 2
  • transforming growth factor, beta receptor IIT
  • transforming growth factor-b type II receptor
  • transforming growth factor-beta receptor type II
  • transforming growth factor-beta type II receptor
  • tgf beta 2
  • transforming growth factor, beta 2
  • milk growth factor
  • transforming growth factor-beta 2
  • transforming growth factor beta-2-like
  • TGF beta 2 protein
  • transforming growth factor-beta2
  • TGF beta 2
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