TPSB2 产品
(Tryptase beta 2 (TPSB2))
Categories
Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability. These genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. The alleles of this gene exhibit an unusual amount of sequence variation, such that the alleles were once thought to represent two separate genes, beta II and beta III. Beta tryptases appear to be the main isoenzymes expressed in mast cells, whereas in basophils, alpha-tryptases predominate. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders. [provided by RefSeq, Jul 2008].
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Featured TPSB2 Categories
TPSB2 抗体
High quality antibodies with extensive validation data.
TPSB2 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
TPSB2 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended TPSB2 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (5)
Cat. No.
ABIN7443440
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Rat
Application
WB, IHC, ICC
Validations
- (4)
Cat. No.
ABIN5014457
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, WB, IHC
Validations
- (2)
Cat. No.
ABIN7173606
Quantity
100 μg
Datasheet
Datasheet
Recommended TPSB2 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6960222
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6970912
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Competition ELISA
Validations
Cat. No.
ABIN454695
Quantity
96 tests
Datasheet
Datasheet
Recommended TPSB2 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7125509
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1323464
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Human Cells
Validations
- (1)
Cat. No.
ABIN7320763
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our TPSB2 Products
: "Mediators of mast cells in bullous pemphigoid and dermatitis herpetiformis." in: Mediators of inflammation, Vol. 2014, pp. 936545, (2014) (PubMed).Synonyms and alternative names related to TPSB2
tryptase beta 2 (gene/pseudogene) (TPSB2), tryptase beta 2 (Tpsb2), Mcpt6, TPS2, tryptaseB, tryptaseCProtein level used designations for TPSB2
- mast cell tryptase beta II
- mast cell tryptase beta III
- tryptase beta-2
- mast cell protease 6
- rMCP-6
- tryptase-2
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