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Topoisomerase II alpha 蛋白

(Topoisomerase (DNA) II alpha 170kDa (TOP2A))
This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This nuclear enzyme is involved in processes such as chromosome condensation, chromatid separation, and the relief of torsional stress that occurs during DNA transcription and replication. It catalyzes the transient breaking and rejoining of two strands of duplex DNA which allows the strands to pass through one another, thus altering the topology of DNA. Two forms of this enzyme exist as likely products of a gene duplication event. The gene encoding this form, alpha, is localized to chromosome 17 and the beta gene is localized to chromosome 3. The gene encoding this enzyme functions as the target for several anticancer agents and a variety of mutations in this gene have been associated with the development of drug resistance. Reduced activity of this enzyme may also play a role in ataxia-telangiectasia. [provided by RefSeq, Jul 2010].
Topoisomerase II alpha Protein (AA 1435-1531) (GST tag) Topoisomerase II alpha Protein (AA 1435-1531) (GST tag) Topoisomerase II alpha Protein (AA 1435-1531) (GST tag) (ABIN1323347)

TOP2A 宿主: 人 宿主: 小麦胚 Recombinant WB, AP, AA, ELISA

Topoisomerase II alpha Protein (AA 1354-1473) Topoisomerase II alpha Protein (AA 1354-1473) Topoisomerase II alpha Protein (AA 1354-1473) (ABIN7013599)

TOP2A 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant >90 % as determined by SDS-PAGE.

Topoisomerase II alpha 蛋白 (ABIN2751809)

TOP2A 宿主: 人, 小鼠, 大鼠 宿主: 大肠杆菌(E. Coli) Recombinant WB, PC

Topoisomerase II alpha 蛋白 by Origin

Find Topoisomerase II alpha 蛋白 for a variety of species such as anti-Human Topoisomerase II alpha, anti-Mouse Topoisomerase II alpha, anti-Rat Topoisomerase II alpha. The species listed below are among those available. Click on a link to go to the corresponding products.

Topoisomerase II alpha 蛋白 by Source

Here you will find Topoisomerase II alpha 蛋白 proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

Topoisomerase II alpha 蛋白 by 蛋白类型

Here you can find Topoisomerase II alpha 蛋白 proteins categorized by available protein types. Additional protein types can be located using our search function.

Topoisomerase II alpha 蛋白 by 应用范围

Find Topoisomerase II alpha 蛋白 validated for a specific application such as WB, AP, AA, ELISA. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular Topoisomerase II alpha 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1323347
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7013599
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN2751809
Quantity 5 applications
Datasheet Datasheet

Aliases for Topoisomerase II alpha 蛋白

DNA topoisomerase II alpha (TOP2A) 蛋白
DNA topoisomerase II, alpha isozyme (Bm1_08705) 蛋白
topoisomerase (DNA) II alpha (Top2a) 蛋白
DNA topoisomerase II alpha (Top2a) 蛋白
topoisomerase (DNA) II alpha (TOP2A) 蛋白
Zincin-like metalloproteases family protein (AT5G10540) 蛋白
DNA topoisomerase II alpha (top2a) 蛋白
F12B17.110 蛋白
F12B17_110 蛋白
fc08c07 蛋白
thimet metalloendopeptidase 2 蛋白
Top-2 蛋白
TOP-2 蛋白
TOP2 蛋白
TOP2A 蛋白
TP2A 蛋白
wu:fc08c07 蛋白
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