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TOP2B 蛋白

(Topoisomerase (DNA) II beta 180kDa (TOP2B))

This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This nuclear enzyme is involved in processes such as chromosome condensation, chromatid separation, and the relief of torsional stress that occurs during DNA transcription and replication. It catalyzes the transient breaking and rejoining of two strands of duplex DNA which allows the strands to pass through one another, thus altering the topology of DNA. Two forms of this enzyme exist as likely products of a gene duplication event. The gene encoding this form, beta, is localized to chromosome 3 and the alpha form is localized to chromosome 17. The gene encoding this enzyme functions as the target for several anticancer agents and a variety of mutations in this gene have been associated with the development of drug resistance. Reduced activity of this enzyme may also play a role in ataxia-telangiectasia. Alternative splicing of this gene results in two transcript variants\; however, the second variant has not yet been fully described. [provided by RefSeq, Jul 2008].

recommended

TOP2B Protein (AA 1411-1523) (GST tag) (ABIN1323349)

TOP2B 宿主: 人宿主: 小麦胚 Recombinant WB, ELISA, AP, AA

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recommended

TOP2B Protein (AA 458-667) (His tag) (ABIN7397666)

TOP2B 宿主: 人宿主: 大肠杆菌（E. Coli） Recombinant > 90 % WB, SDS, Imm, PC

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recommended

TOP2B Protein (AA 446-655) (His tag) (ABIN7406401)

TOP2B 宿主: 小鼠宿主: 大肠杆菌（E. Coli） Recombinant > 95 % WB, SDS, Imm, PC

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TOP2B 蛋白 by Origin

Find TOP2B 蛋白 for a variety of species such as anti-Human TOP2B, anti-Mouse TOP2B. The species listed below are among those available. Click on a link to go to the corresponding products.

TOP2B 蛋白 by Source

Here you will find TOP2B 蛋白 proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

TOP2B 蛋白 by 蛋白类型

Here you can find TOP2B 蛋白 proteins categorized by available protein types. Additional protein types can be located using our search function.

TOP2B 蛋白 by 应用范围

Find TOP2B 蛋白 validated for a specific application such as WB, SDS, ELISA, Imm. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular TOP2B 蛋白

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

TOP2B Protein (AA 1411-1523) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1323349

Quantity 10 μg

Datasheet Datasheet

TOP2B Protein (AA 458-667) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7397666

Quantity 100 μg

Datasheet Datasheet

TOP2B Protein (AA 446-655) (His tag)

Reactivity Mouse

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7406401

Quantity 100 μg

Datasheet Datasheet

TOP2B 蛋白

Reactivity Mouse

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN3011939

Quantity 100 μg

Datasheet Datasheet

TOP2B 蛋白

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN6126495

Quantity 100 μg

Datasheet Datasheet

Aliases for TOP2B 蛋白

DNA topoisomerase II beta (TOP2B) 蛋白
topoisomerase (DNA) II beta (Top2b) 蛋白
DNA topoisomerase II beta (Top2b) 蛋白
microRNA 4442 (MIR4442) 蛋白
D230016L12Rik 蛋白
Top-2 蛋白
TOP2B 蛋白
top2beta 蛋白
TOPIIB 蛋白

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TOP2B 蛋白 by Origin

TOP2B 蛋白 by Source

TOP2B 蛋白 by 蛋白类型

TOP2B 蛋白 by 应用范围

Popular TOP2B 蛋白

Aliases for TOP2B 蛋白

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