TNNI1 抗体
(Slow Skeletal Troponin I (TNNI1))
Troponin proteins associate with tropomyosin and regulate the calcium sensitivity of the myofibril contractile apparatus of striated muscles. Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit\; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. The TnI-fast and TnI-slow genes are expressed in fast-twitch and slow-twitch skeletal muscle fibers, respectively, while the TnI-cardiac gene is expressed exclusively in cardiac muscle tissue. This gene encodes the Troponin-I-skeletal-slow-twitch protein. This gene is expressed in cardiac and skeletal muscle during early development but is restricted to slow-twitch skeletal muscle fibers in adults. The encoded protein prevents muscle contraction by inhibiting calcium-mediated conformational changes in actin-myosin complexes. [provided by RefSeq, Jul 2008].
recommended
recommended
TNNI1 适用: 人, 大鼠, 小鼠, Cow, 山羊, 犬, 豚鼠, 马, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
recommended
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Reactivity
Application
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Cat. No.
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Datasheet
Reactivity
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Application
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Cat. No.
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Quantity
100 μL
Datasheet
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Reactivity
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Application
WB, IHC
Validations
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Quantity
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Datasheet
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Quantity
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Datasheet
Datasheet
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Quantity
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Datasheet
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Datasheet
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Datasheet
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Datasheet
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Quantity
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Datasheet
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Datasheet
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Quantity
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Datasheet
Datasheet
Reactivity
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Validations
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Quantity
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Datasheet
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Latest Publications for our TNNI1 抗体
: "Dietary leucine supplementation alters energy metabolism and induces slow-to-fast transitions in longissimus dorsi muscle of weanling piglets." in: The British journal of nutrition, Vol. 117, Issue 9, pp. 1222-1234, (2017) (PubMed).: "Myogenic differentiation potential of human tonsil-derived mesenchymal stem cells and their potential for use to promote skeletal muscle regeneration." in: International journal of molecular medicine, Vol. 37, Issue 5, pp. 1209-20, (2016) (PubMed).
: "Myostatin deficiency but not anti-myostatin blockade induces marked proteomic changes in mouse skeletal muscle." in: Proteomics, Vol. 16, Issue 14, pp. 2019-27, (2016) (PubMed).
: "Dietary L-arginine supplementation affects the skeletal longissimus muscle proteome in finishing pigs." in: PLoS ONE, Vol. 10, Issue 1, pp. e0117294, (2015) (PubMed).
: "Troponin-like regulation in muscle thin filaments of the mussel Crenomytilus grayanus (Bivalvia: Mytiloida)." in: Biochimica et biophysica acta, Vol. 1854, Issue 10 Pt A, pp. 1444-50, (2015) (PubMed).
: "Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells." in: Nature methods, Vol. 10, Issue 4, pp. 315-23, (2013) (PubMed).
: "Tbx20 promotes cardiomyocyte proliferation and persistence of fetal characteristics in adult mouse hearts." in: Journal of molecular and cellular cardiology, Vol. 62, pp. 203-13, (2013) (PubMed).
: "Myocardial Mycn is essential for mouse ventricular wall morphogenesis." in: Developmental biology, Vol. 373, Issue 1, pp. 53-63, (2012) (PubMed).
: "Identification of a region of troponin I important in signaling cross-bridge-dependent activation of cardiac myofilaments." in: The Journal of biological chemistry, Vol. 282, Issue 1, pp. 183-93, (2007) (PubMed).
: "Relationship between anemia, cardiac troponin I, and B-type natriuretic peptide levels and mortality in patients with advanced heart failure." in: American heart journal, Vol. 150, Issue 6, pp. 1220-7, (2005) (PubMed).
Aliases for TNNI1 抗体
troponin T1, slow skeletal type (TNNT1) 抗体troponin I1, slow skeletal type (TNNI1) 抗体
troponin I, skeletal, slow 1 (Tnni1) 抗体
troponin I1, slow skeletal type (Tnni1) 抗体
troponin T1, skeletal, slow (Tnnt1) 抗体
troponin T1, slow skeletal type (Tnnt1) 抗体
troponin I1, slow skeletal type S homeolog (tnni1.S) 抗体
troponin I type 1 (skeletal, slow) (TNNI1) 抗体
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