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TNK1 抗体

(Tyrosine Kinase, Non-Receptor, 1 (TNK1))
The protein encoded by this gene belongs to the tyrosine protein kinase family. Tyrosine protein kinases are important regulators of intracellular signal transduction pathways, mediating cellular proliferation, survival, and development. This gene is highly expressed in fetal tissues and at lower levels in few adult tissues, thus may function in signaling pathways utilized broadly during fetal development, and more selectively in adult tissues. It plays a negative regulatory role in the Ras-Raf1-MAPK pathway, and knockout mice have been shown to develop spontaneous tumors, suggesting a role as a tumor suppressor gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011].
TNK1 抗体 TNK1 抗体 TNK1 抗体 (ABIN7192841)

TNK1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

TNK1 抗体  (AA 451-560) TNK1 抗体  (AA 451-560) TNK1 抗体 (AA 451-560) (ABIN1724711)

TNK1 适用: 人 ELISA 宿主: 小鼠 Monoclonal 1B5G3 unconjugated

TNK1 抗体  (AA 256-286) TNK1 抗体  (AA 256-286) TNK1 抗体 (AA 256-286) (ABIN392113)

TNK1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB3104 unconjugated

TNK1 抗体 by 适用

Find TNK1 抗体 for a variety of species such as anti-Human TNK1, anti-Mouse TNK1, anti-Guinea Pig TNK1. The species listed below are among those available. Click on a link to go to the corresponding products.

TNK1 抗体 by 应用范围

Find TNK1 抗体 validated for a specific application such as WB, ELISA, IHC, IF (cc). Some of the available applications are listed below. Click on a link to go to the corresponding products.

TNK1 抗体 by 抗体来源

Find TNK1 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

TNK1 抗体 by 抗原表位

Find TNK1 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

TNK1 抗体 by 克隆形成能力

Find available monoclonal or polyclonal TNK1 抗体. Click on a link to go to the corresponding products.

TNK1 抗体 by 克隆

Find TNK1 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

TNK1 抗体 by 标记

Find TNK1 抗体 with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular TNK1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7192841
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
  • (2)
  • (1)
Cat. No. ABIN1724711
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (1)
  • (2)
Cat. No. ABIN392113
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN3029412
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Mouse
Application WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC
Validations
  • (1)
Cat. No. ABIN746513
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN6243295
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IHC (p)
Validations
  • (1)
Cat. No. ABIN6755294
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN3029413
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p), EIA
Validations
  • (2)
Cat. No. ABIN359998
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human
Application ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
Cat. No. ABIN701215
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC (p), IHC (fro)
Validations
Cat. No. ABIN701217
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC (p)
Validations
Cat. No. ABIN4914758
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IF (cc), IF (p)
Validations
Cat. No. ABIN2807118
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IF (cc), IF (p)
Validations
Cat. No. ABIN5011789
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IF (cc), IF (p)
Validations
Cat. No. ABIN918200
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our TNK1 抗体

Henderson, Gonzales, Arora, Choudhary, Trent, Von Hoff, Mousses, Azorsa: "High-throughput RNAi screening identifies a role for TNK1 in growth and survival of pancreatic cancer cells." in: Molecular cancer research : MCR, Vol. 9, Issue 6, pp. 724-32, (2011) (PubMed).

Azoitei, Brey, Busch, Fulda, Adler, Seufferlein: "Thirty-eight-negative kinase 1 (TNK1) facilitates TNFalpha-induced apoptosis by blocking NF-kappaB activation." in: Oncogene, Vol. 26, Issue 45, pp. 6536-45, (2007) (PubMed).

Gerhard, Wagner, Feingold, Shenmen, Grouse, Schuler, Klein, Old, Rasooly, Good, Guyer, Peck, Derge, Lipman, Collins, Jang, Sherry, Feolo, Misquitta, Lee, Rotmistrovsky, Greenhut, Schaefer, Buetow et al.: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). ..." in: Genome research, Vol. 14, Issue 10B, pp. 2121-7, (2004) (PubMed).

Hoare, Hoare, Smith, Kalmaz, Small, Stratford May: "Kos1, a nonreceptor tyrosine kinase that suppresses Ras signaling." in: Oncogene, Vol. 22, Issue 23, pp. 3562-77, (2003) (PubMed).

Cantrell: "Phosphoinositide 3-kinase signalling pathways." in: Journal of cell science, Vol. 114, Issue Pt 8, pp. 1439-45, (2001) (PubMed).

Blume-Jensen, Hunter: "Oncogenic kinase signalling." in: Nature, Vol. 411, Issue 6835, pp. 355-65, (2001) (PubMed).

Jhiang: "The RET proto-oncogene in human cancers." in: Oncogene, Vol. 19, Issue 49, pp. 5590-7, (2000) (PubMed).

Felschow, Civin, Hoehn: "Characterization of the tyrosine kinase Tnk1 and its binding with phospholipase C-gamma1." in: Biochemical and biophysical research communications, Vol. 273, Issue 1, pp. 294-301, (2000) (PubMed).

Aliases for TNK1 抗体

tyrosine kinase non receptor 1 (TNK1) 抗体
tyrosine kinase, non-receptor, 1 (Tnk1) 抗体
tyrosine kinase non receptor 1 (Tnk1) 抗体
Ack-like 抗体
Kos1 抗体
Tnk1a 抗体
Tnk1b 抗体
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