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TNFSF18 产品

(Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18))

Categories

The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF18/AITR/GITR. It has been shown to modulate T lymphocyte survival in peripheral tissues. This cytokine is also found to be expressed in endothelial cells, and is thought to be important for interaction between T lymphocytes and endothelial cells. [provided by RefSeq, Jul 2008].

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Featured TNFSF18 Categories

TNFSF18 抗体

High quality antibodies with extensive validation data.

TNFSF18 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

TNFSF18 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended TNFSF18 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IF (p), IF (cc), IHC (p), IHC (fro)
Validations
  • (6)
Cat. No. ABIN740535
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IP
Validations
  • (3)
Cat. No. ABIN522440
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (4)
Cat. No. ABIN5519067
Quantity 100 μg
Datasheet Datasheet

Recommended TNFSF18 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6970947
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (1)
Cat. No. ABIN625249
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN1889448
Quantity 96 tests
Datasheet Datasheet

Recommended TNFSF18 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (4)
Cat. No. ABIN7274682
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7274681
Quantity 100 μg
Datasheet Datasheet
Reactivity Cynomolgus
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7274678
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our TNFSF18 Products

Gan, Feng, Gu, Tan, Sun, Lv, Zhang: "Correlation of increased blood levels of GITR and GITRL with disease severity in patients with primary Sjögren's syndrome." in: Clinical & developmental immunology, Vol. 2013, pp. 340751, (2013) (PubMed).

Wang, Yi, Qin, Maldonado, von Andrian, Kulkarni, Tellides, Pober: "Rapamycin-treated human endothelial cells preferentially activate allogeneic regulatory T cells." in: The Journal of clinical investigation, Vol. 123, Issue 4, pp. 1677-93, (2013) (PubMed).

Schmiedel, Werner, Steinbacher, Nuebling, Buechele, Grosse-Hovest, Salih: "Generation and preclinical characterization of a Fc-optimized GITR-Ig fusion protein for induction of NK cell reactivity against leukemia." in: Molecular therapy : the journal of the American Society of Gene Therapy, Vol. 21, Issue 4, pp. 877-86, (2013) (PubMed).

Gu, Xu, Zhang, Tan, Wang, Zhang: "Correlation of circulating glucocorticoid-induced TNFR-related protein ligand levels with disease activity in patients with systemic lupus erythematosus." in: Clinical & developmental immunology, Vol. 2012, pp. 265868, (2012) (PubMed).

Piao, Kamimura, Iwai, Cao, Kikuchi, Hashiguchi, Masunaga, Jiang, Tamura, Sakaguchi, Azuma: "Enhancement of T-cell-mediated anti-tumour immunity via the ectopically expressed glucocorticoid-induced tumour necrosis factor receptor-related receptor ligand (GITRL) on tumours." in: Immunology, Vol. 127, Issue 4, pp. 489-99, (2009) (PubMed).

Sakihama, Sato, Iwanari, Kitamura, Sakaguchi, Kodama, Hamakubo: "A simple detection method for low-affinity membrane protein interactions by baculoviral display." in: PLoS ONE, Vol. 3, Issue 12, pp. e4024, (2008) (PubMed).

Igarashi, Cao, Iwai, Piao, Kamimura, Hashiguchi, Amagasa, Azuma: "GITR ligand-costimulation activates effector and regulatory functions of CD4+ T cells." in: Biochemical and biophysical research communications, Vol. 369, Issue 4, pp. 1134-8, (2008) (PubMed).

Han, ONeil-Andersen, Zurier, Lawrence: "CD4+CD25high T cell numbers are enriched in the peripheral blood of patients with rheumatoid arthritis." in: Cellular immunology, Vol. 253, Issue 1-2, pp. 92-101, (2008) (PubMed).

Baltz, Krusch, Baessler, Schmiedel, Bringmann, Brossart, Salih: "Neutralization of tumor-derived soluble glucocorticoid-induced TNFR-related protein ligand increases NK cell anti-tumor reactivity." in: Blood, Vol. 112, Issue 9, pp. 3735-43, (2008) (PubMed).

Baltz, Krusch, Bringmann, Brossart, Mayer, Kloss, Baessler, Kumbier, Peterfi, Kupka, Kroeber, Menzel, Radsak, Rammensee, Salih: "Cancer immunoediting by GITR (glucocorticoid-induced TNF-related protein) ligand in humans: NK cell/tumor cell interactions." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 21, Issue 10, pp. 2442-54, (2007) (PubMed).

Synonyms and alternative names related to TNFSF18

tumor necrosis factor (ligand) superfamily, member 18 (Tnfsf18), TNF superfamily member 18 (TNFSF18), TNF superfamily member 18 (Tnfsf18), AITRL, Gitrl, GITRL, hGITRL, TL6, TNLG2A

Protein level used designations for TNFSF18

  • GITR ligand
  • glucocorticoid-induced TNF-related ligand
  • glucocorticoid-induced-tumor necrosis factor receptor ligand
  • tumor necrosis factor ligand superfamily member 18
  • AITR ligand
  • activation-inducible TNF-related ligand
  • glucocorticoid-induced TNFR-related protein ligand
  • tumor necrosis factor (ligand) superfamily, member 18
  • tumor necrosis factor ligand 2A
  • tumor necrosis factor superfamily member 18
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