TNFRSF13C 产品
(Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C))
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B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival. [provided by RefSeq, Jul 2008].
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Featured TNFRSF13C Categories
TNFRSF13C 抗体
High quality antibodies with extensive validation data.
TNFRSF13C ELISA试剂盒
Reliable ELISA kits for a wide range of species.
TNFRSF13C 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended TNFRSF13C 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Rat
Application
WB, ELISA, FACS, IHC, ICC, Neut
Validations
- (5)
Cat. No.
ABIN5611148
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, FACS, IHC, ICC, Neut
Validations
- (4)
Cat. No.
ABIN5611147
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
WB
Validations
- (2)
Cat. No.
ABIN530345
Quantity
100 μg
Datasheet
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Recommended TNFRSF13C ELISA试剂盒
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Cat. No.
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Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
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- (1)
Cat. No.
ABIN6960290
Quantity
96 tests
Datasheet
Datasheet
Reactivity
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Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6970978
Quantity
96 tests
Datasheet
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Reactivity
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Analytical Method
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Validations
- (1)
Cat. No.
ABIN1706072
Quantity
96 tests
Datasheet
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Recommended TNFRSF13C 蛋白
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Source
HEK-293 Cells
Validations
- (5)
Cat. No.
ABIN7273910
Quantity
100 μg
Datasheet
Datasheet
Reactivity
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Source
HEK-293 Cells
Validations
- (5)
Cat. No.
ABIN7273915
Quantity
100 μg
Datasheet
Datasheet
Reactivity
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Source
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Validations
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Cat. No.
ABIN7273912
Quantity
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Latest Publications for our TNFRSF13C Products
: "Characterization of B cells in lupus erythematosus skin biopsies in the context of different immune cell infiltration patterns." in: Frontiers in medicine, Vol. 9, pp. 1037408, (2022) (PubMed).: "B-Lymphocyte Phenotype Determines T-Lymphocyte Subset Differentiation in Autoimmune Diabetes." in: Frontiers in immunology, Vol. 10, pp. 1732, (2019) (PubMed).
: "B cell activating factor (BAFF) selects IL-10(-)B cells over IL-10(+)B cells during inflammatory responses." in: Molecular immunology, Vol. 85, pp. 18-26, (2017) (PubMed).
: "The BAFF receptor TACI controls IL-10 production by regulatory B cells and CLL B cells." in: Leukemia, Vol. 30, Issue 1, pp. 163-72, (2016) (PubMed).
: "Human B cells induce dendritic cell maturation and favour Th2 polarization by inducing OX-40 ligand." in: Nature communications, Vol. 5, pp. 4092, (2014) (PubMed).
: "Soluble BAFF-R produced by decidual stromal cells plays an inhibitory role in monocytes and macrophages." in: Reproductive biomedicine online, Vol. 24, Issue 6, pp. 654-63, (2012) (PubMed).
: "BAFF-R expression correlates with positive selection of immature B cells." in: European journal of immunology, Vol. 42, Issue 1, pp. 206-16, (2012) (PubMed).
: "APRIL binding to BCMA activates a JNK2-FOXO3-GADD45 pathway and induces a G2/M cell growth arrest in liver cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 189, Issue 10, pp. 4748-58, (2012) (PubMed).
: "BAFF levels are increased in lesional skin and sera in patients with cutaneous T-cell lymphoma." in: The British journal of dermatology, Vol. 167, Issue 2, pp. 359-67, (2012) (PubMed).
: "Fusion toxin BLyS-gelonin inhibits growth of malignant human B cell lines in vitro and in vivo." in: PLoS ONE, Vol. 7, Issue 10, pp. e47361, (2012) (PubMed).
Synonyms and alternative names related to TNFRSF13C
TNF receptor superfamily member 13C (TNFRSF13C), TNF receptor superfamily member 13C (Tnfrsf13c), uncharacterized LOC746611 (LOC746611), tumor necrosis factor receptor superfamily, member 13c (Tnfrsf13c), 2010006P15Rik, BAFF-R, BAFFR, Baffr, Bcmd, Bcmd-1, Bcmd1, BROMIX, CD268, CVID4, Lvis22, prolixin, RGD1560810, TNFRSF13CProtein level used designations for TNFRSF13C
- tumor necrosis factor receptor superfamily, member 13C
- tumor necrosis factor receptor superfamily member 13C
- B cell-activating factor receptor
- B-cell-activating factor receptor
- BAFF receptor
- BLyS receptor 3
- B-cell maturation defect 1
- b cell-activating factor receptor
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