TNFRSF10A 产品
(Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A))
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The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. [provided by RefSeq, Jul 2008].
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Featured TNFRSF10A Categories
TNFRSF10A 抗体
High quality antibodies with extensive validation data.
TNFRSF10A ELISA试剂盒
Reliable ELISA kits for a wide range of species.
TNFRSF10A 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended TNFRSF10A 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
FACS, IP, ICC
Validations
- (1)
- (2)
Cat. No.
ABIN2749053
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (3)
Cat. No.
ABIN6149301
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (3)
Cat. No.
ABIN6149302
Quantity
100 μL
Datasheet
Datasheet
Recommended TNFRSF10A ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6970966
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6960277
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN625358
Quantity
96 tests
Datasheet
Datasheet
Recommended TNFRSF10A 蛋白
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Reactivity
Source
Validations
Cat. No.
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Reactivity
Human
Source
HEK-293 Cells
Validations
- (5)
Cat. No.
ABIN7275778
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7275776
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7275777
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our TNFRSF10A Products
: "Accelerated degradation of cFLIPL and sensitization of the TRAIL DISC-mediated apoptotic cascade by pinoresinol, a lignan isolated from Rubia philippinensis." in: Scientific reports, Vol. 9, Issue 1, pp. 13505, (2019) (PubMed).: "High-efficiency antibody discovery achieved with multiplexed microscopy." in: Microscopy (Oxford, England), Vol. 65, Issue 4, pp. 341-52, (2018) (PubMed).
: "CGP57380 enhances efficacy of RAD001 in non-small cell lung cancer through abrogating mTOR inhibition-induced phosphorylation of eIF4E and activating mitochondrial apoptotic pathway." in: Oncotarget, Vol. 7, Issue 19, pp. 27787-801, (2016) (PubMed).
: "NVP-BKM120 potentiates apoptosis in tumor necrosis factor-related apoptosis-inducing ligand-resistant glioma cell lines via upregulation of Noxa and death receptor 5." in: International journal of oncology, Vol. 47, Issue 2, pp. 506-16, (2015) (PubMed).
: "The role of selected flavonols in tumor necrosis factor-related apoptosis-inducing ligand receptor-1 (TRAIL-R1) expression on activated RAW 264.7 macrophages." in: Molecules (Basel, Switzerland), Vol. 20, Issue 1, pp. 900-12, (2015) (PubMed).
: "Caspase-8 expression is predictive of tumour response to death receptor 5 agonist antibody in Ewing's sarcoma." in: British journal of cancer, Vol. 113, Issue 6, pp. 894-901, (2015) (PubMed).
: "miR-942 decreases TRAIL-induced apoptosis through ISG12a downregulation and is regulated by AKT." in: Oncotarget, Vol. 5, Issue 13, pp. 4959-71, (2014) (PubMed).
: "Dominant negative effects of tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) receptor 4 on TRAIL receptor 1 signaling by formation of heteromeric complexes." in: The Journal of biological chemistry, Vol. 289, Issue 23, pp. 16576-87, (2014) (PubMed).
: "Potential application of temozolomide in mesenchymal stem cell-based TRAIL gene therapy against malignant glioma." in: Stem cells translational medicine, Vol. 3, Issue 2, pp. 172-82, (2014) (PubMed).
: "Early and nonreversible decrease of CD161++ /MAIT cells in HIV infection." in: Blood, Vol. 121, Issue 6, pp. 951-61, (2013) (PubMed).
Synonyms and alternative names related to TNFRSF10A
TNF receptor superfamily member 10a (TNFRSF10A), tumor necrosis factor receptor superfamily member 26 (LOC510798), tumor necrosis factor receptor superfamily, member 10a (TNFRSF10A), APO2, CD261, DR4, TNFRSF10A, TRAILR-1, TRAILR1Protein level used designations for TNFRSF10A
- TNF-related apoptosis-inducing ligand receptor 1
- TRAIL receptor 1
- TRAIL-R1
- cytotoxic TRAIL receptor
- death receptor 4
- tumor necrosis factor receptor superfamily member 10A
- tumor necrosis factor receptor superfamily member 10a variant 2
- tumor necrosis factor receptor superfamily, member 10a
- tumor necrosis factor receptor superfamily member 10A-like
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