TMED10 产品
(Transmembrane Emp24-Like Trafficking Protein 10 (TMED10))
Categories
This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8. [provided by RefSeq, Jul 2008].
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Featured TMED10 Categories
Recommended TMED10 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC
Validations
- (2)
Cat. No.
ABIN1386483
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IF, FACS
Validations
- (2)
Cat. No.
ABIN190858
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Chicken, Cow, Dog, Guinea Pig, Hamster, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat, Xenopus laevis, Zebrafish (Danio rerio)
Application
WB
Validations
- (1)
Cat. No.
ABIN6744308
Quantity
100 μL
Datasheet
Datasheet
Recommended TMED10 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN6387259
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our TMED10 Products
: "TMP21 is a presenilin complex component that modulates gamma-secretase but not epsilon-secretase activity." in: Nature, Vol. 440, Issue 7088, pp. 1208-12, (2006) (PubMed).: "Functional reconstitution of gamma-secretase through coordinated expression of presenilin, nicastrin, Aph-1, and Pen-2." in: Journal of neuroscience research, Vol. 77, Issue 3, pp. 309-22, (2004) (PubMed).
: "The cell biology of beta-amyloid precursor protein and presenilin in Alzheimer's disease." in: Trends in cell biology, Vol. 8, Issue 11, pp. 447-53, (1999) (PubMed).
Synonyms and alternative names related to TMED10
transmembrane p24 trafficking protein 10 L homeolog (tmed10.L), transmembrane p24 trafficking protein 10 (TMED10), transmembrane p24 trafficking protein 10 (Tmed10), transmembrane p24 trafficking protein 10 (tmed10), 1110014C03Rik, fe06g04, p23, P24(DELTA), p24delta1, S31I125, S31III125, Tmp-21-I, tmp21, TMP21, Tmp21, wu:fb98e10, wu:fe06g04, zgc:85681Protein level used designations for TMED10
- transmembrane protein tmp21
- 21 kDa transmembrane trafficking protein
- 21 kDa transmembrane-trafficking protein
- p24 family protein delta-1
- p24delta
- p24delta1
- transmembrane emp24 domain-containing protein 10
- transmembrane protein Tmp21
- transmembrane trafficking protein
- integral membrane protein Tmp21-I (p23)
- transmembrane trafficking protein 21
- p24 delta 1
- integral membrane protein p23
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