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TMC8 产品

(Transmembrane Channel-Like 8 (TMC8))

Categories

Epidermodysplasia verruciformis (EV) is an autosomal recessive dermatosis characterized by abnormal susceptibility to human papillomaviruses (HPVs) and a high rate of progression to squamous cell carcinoma on sun-exposed skin. EV is caused by mutations in either of two adjacent genes located on chromosome 17q25.3. Both of these genes encode integral membrane proteins that localize to the endoplasmic reticulum and are predicted to form transmembrane channels. This gene encodes a transmembrane channel-like protein with 8 predicted transmembrane domains and 3 leucine zipper motifs. [provided by RefSeq, Jul 2008].

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Featured TMC8 Categories

TMC8 抗体

High quality antibodies with extensive validation data.

TMC8 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended TMC8 抗体

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Reactivity
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Datasheet
Reactivity Human
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Cat. No. ABIN7185610
Quantity 100 μg
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Reactivity Human, Mouse, Rat
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Cat. No. ABIN3187286
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Cat. No. ABIN6265610
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Recommended TMC8 蛋白

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Source Tobacco (Nicotiana tabacum)
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Cat. No. ABIN3116276
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Reactivity Mouse
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Cat. No. ABIN3124052
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Latest Publications for our TMC8 Products

Lazarczyk, Pons, Mendoza, Cassonnet, Jacob, Favre: "Regulation of cellular zinc balance as a potential mechanism of EVER-mediated protection against pathogenesis by cutaneous oncogenic human papillomaviruses." in: The Journal of experimental medicine, Vol. 205, Issue 1, pp. 35-42, (2008) (PubMed).

Ramoz, Rueda, Bouadjar, Montoya, Orth, Favre: "Mutations in two adjacent novel genes are associated with epidermodysplasia verruciformis." in: Nature genetics, Vol. 32, Issue 4, pp. 579-81, (2002) (PubMed).

Ramoz, Taïeb, Rueda, Montoya, Bouadjar, Favre, Orth: "Evidence for a nonallelic heterogeneity of epidermodysplasia verruciformis with two susceptibility loci mapped to chromosome regions 2p21-p24 and 17q25." in: The Journal of investigative dermatology, Vol. 114, Issue 6, pp. 1148-53, (2000) (PubMed).

Synonyms and alternative names related to TMC8

transmembrane channel like 8 (TMC8), transmembrane channel-like 8 (Tmc8), transmembrane channel-like gene family 8 (Tmc8), EV2, EVER2, Ever2, EVIN2, mFLJ00400

Protein level used designations for TMC8

  • transmembrane channel-like 8
  • FLJ00400 protein-like
  • transmembrane channel-like protein 8-like
  • epidermodysplasia verruciformis 2
  • epidermodysplasia verruciformis protein 2
  • transmembrane channel-like protein 8
  • uncharacterized protein LOC688276
  • epidermodysplasia verruciformis protein 2 homolog
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