TMC6 产品
(Transmembrane Channel-Like 6 (TMC6))
Categories
Epidermodysplasia verruciformis (EV) is an autosomal recessive dermatosis characterized by abnormal susceptibility to human papillomaviruses (HPVs) and a high rate of progression to squamous cell carcinoma on sun-exposed skin. EV is caused by mutations in either of two adjacent genes located on chromosome 17q25.3. Both of these genes encode integral membrane proteins that localize to the endoplasmic reticulum and are predicted to form transmembrane channels. This gene encodes a transmembrane channel-like protein with 10 transmembrane domains and 2 leucine zipper motifs. [provided by RefSeq, Jul 2008].
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Featured TMC6 Categories
Recommended TMC6 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC (p), EIA
Validations
- (2)
Cat. No.
ABIN499806
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IHC (p), IF
Validations
Cat. No.
ABIN6990885
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC (p)
Validations
Cat. No.
ABIN6990884
Quantity
0.1 mg
Datasheet
Datasheet
Recommended TMC6 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1322912
Quantity
25 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3124055
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3116040
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our TMC6 Products
: "EVER proteins, key elements of the natural anti-human papillomavirus barrier, are regulated upon T-cell activation." in: PLoS ONE, Vol. 7, Issue 6, pp. e39995, (2013) (PubMed).: "Regulation of cellular zinc balance as a potential mechanism of EVER-mediated protection against pathogenesis by cutaneous oncogenic human papillomaviruses." in: The Journal of experimental medicine, Vol. 205, Issue 1, pp. 35-42, (2008) (PubMed).
: "TMC and EVER genes belong to a larger novel family, the TMC gene family encoding transmembrane proteins." in: BMC genomics, Vol. 4, Issue 1, pp. 24, (2003) (PubMed).
Synonyms and alternative names related to TMC6
transmembrane channel like 6 (TMC6), transmembrane channel-like 6b (tmc6b), transmembrane channel like 6 L homeolog (tmc6.L), transmembrane channel like 6 (tmc6), transmembrane channel-like gene family 6 (Tmc6), D11Ertd204e, EV1, EVER1, ever1, EVIN1, LAK-4P, MGC83549, zgc:92610Protein level used designations for TMC6
- transmembrane channel-like 6
- epidermodysplasia verruciformis 1
- transmembrane channel-like protein 6
- transmembrane channel-like protein 6-like
- epidermodysplasia verruciformis protein 1
- expressed in activated T/LAK lymphocytes
- protein LAK-4
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