TLR4 产品
(Toll-Like Receptor 4 (TLR4))
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The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012].
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Featured TLR4 Categories
TLR4 抗体
High quality antibodies with extensive validation data.
TLR4 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
TLR4 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended TLR4 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Cow, Human, Mouse, Rat
Application
WB, FACS, ELISA, IHC (p), IF (p), IF (cc), IHC (fro)
Validations
- (13)
- (8)
Cat. No.
ABIN736491
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, FACS, IHC, IF, ICC
Validations
- (3)
- (6)
Cat. No.
ABIN361724
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Rat
Application
WB, IHC, IP, ICC
Validations
- (7)
Cat. No.
ABIN7432529
Quantity
100 μL
Datasheet
Datasheet
Recommended TLR4 ELISA试剂盒
Product
Reactivity
Analytical Method
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Cat. No.
Quantity
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Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (20)
- (6)
Cat. No.
ABIN6574197
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (16)
- (1)
Cat. No.
ABIN6960033
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (2)
- (1)
Cat. No.
ABIN6963242
Quantity
96 tests
Datasheet
Datasheet
Recommended TLR4 蛋白
Latest Publications for our TLR4 Products
: "Neuroprotective Effects of Ethyl Pyruvate against Aluminum Chloride-Induced Alzheimer's Disease in Rats via Inhibiting Toll-Like Receptor 4." in: Journal of molecular neuroscience : MN, Vol. 70, Issue 6, pp. 836-850, (2021) (PubMed).: "Insight Into Polysaccharides From Panax ginseng C. A. Meyer in Improving Intestinal Inflammation: Modulating Intestinal Microbiota and Autophagy." in: Frontiers in immunology, Vol. 12, pp. 683911, (2021) (PubMed).
: "Magnesium Isoglycyrrhizinate Alleviates Arsenic Trioxide-Induced Cardiotoxicity: Contribution of Nrf2 and TLR4/NF-κB Signaling Pathway." in: Drug design, development and therapy, Vol. 15, pp. 543-556, (2021) (PubMed).
: "Ischemic postconditioning ameliorates acute kidney injury induced by limb ischemia/reperfusion via transforming TLR4 and NF-κB signaling in rats." in: Journal of orthopaedic surgery and research, Vol. 16, Issue 1, pp. 416, (2021) (PubMed).
: "Sulforaphane elicts dual therapeutic effects on Renal Inflammatory Injury and crystal deposition in Calcium Oxalate Nephrocalcinosis." in: Theranostics, Vol. 10, Issue 16, pp. 7319-7334, (2021) (PubMed).
: "Shaoyao-Gancao Decoction Ameliorates the Inflammation State in Polycystic Ovary Syndrome Rats via Remodeling Gut Microbiota and Suppressing the TLR4/NF-κB Pathway." in: Frontiers in pharmacology, Vol. 12, pp. 670054, (2021) (PubMed).
: "The effect of high mobility group box-1 protein on cerebral edema, blood-brain barrier, oxidative stress and apoptosis in an experimental traumatic brain injury model." in: Brain research bulletin, Vol. 154, pp. 68-80, (2020) (PubMed).
: "Deregulation of TLR4 signaling pathway characterizes Bicuspid Aortic valve syndrome." in: Scientific reports, Vol. 9, Issue 1, pp. 11028, (2020) (PubMed).
: "Circulating microbiota-derived metabolites: a "liquid biopsy?" in: International journal of obesity (2005), Vol. 44, Issue 4, pp. 875-885, (2020) (PubMed).
: "Particulate Shiga Toxin 2 in Blood is Associated to the Development of Hemolytic Uremic Syndrome in Children." in: Thrombosis and haemostasis, Vol. 120, Issue 1, pp. 107-120, (2020) (PubMed).
Synonyms and alternative names related to TLR4
toll like receptor 4 (TLR4), toll-like receptor 4 (Tlr4), toll like receptor 4 (Tlr4), ARMD10, CD284, Lps, Ly87, Ran/M1, Rasl2-8, TLR-4, TOLLProtein level used designations for TLR4
- hToll
- homolog of Drosophila toll
- lipopolysaccharide response
- toll4
- Toll-like receptor4 protein
- Toll-like receptor 4-like protein
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